D724-0385 Screening compound: 5-tert-butyl-3-phenyl-N-[(pyridin-2-yl)methyl]pyrazolo[1,5-a]pyrimidin-7-amine

D724-0385 Screening compound: 5-tert-butyl-3-phenyl-N-[(pyridin-2-yl)methyl]pyrazolo[1,5-a]pyrimidin-7-amine
D724-0385 Screening compound: 5-tert-butyl-3-phenyl-N-[(pyridin-2-yl)methyl]pyrazolo[1,5-a]pyrimidin-7-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound D724-0385
5-tert-butyl-3-phenyl-N-[(pyridin-2-yl)methyl]pyrazolo[1,5-a]pyrimidin-7-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D724-0385

Molecular Formula

C22H23N5 (C22 H23 N5)

Compound Name

5-tert-butyl-3-phenyl-N-[(pyridin-2-yl)methyl]pyrazolo[1,5-a]pyrimidin-7-amine

IUPAC name

5-tert-butyl-3-phenyl-N-[(pyridin-2-yl)methyl]pyrazolo[15-a]pyrimidin-7-amine

SMILES

CC(C)(C)c(cc(NCc1ncccc1)n1nc2)nc1c2-c1ccccc1

InChI

InChI=1S/C22H23N5/c1-22(2,3)19-13-20(24-14-17-11-7-8-12-23-17)27-21(26-19)18(15-25-27)16-9-5-4-6-10-16/h4-13,15,24H,14H2,1-3H3

InChI Key

JMJYOTIXZUULGK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD06601971

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

357.46

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.702

Distribution Coefficient, logD

3.556

Water Solubility, LogSw

-4.37

Polar Surface Area

40.286

Acid Dissociation Constant (pKa)

17.03

Base Dissociation Constant (pKb)

8.51

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.70

D724-0385 in Drug Discovery

Included in Screening Libraries

Antiviral Annotated Library (21441 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Voltage-Gated Ion Channel-Targeted Library (4740 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Nervous system
Targets:
  • Proteases
  • Ion Channels

References: we are preparing a list of scientific research reports with D724-0385 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D724-0385?
Check Price and Availability of D724-0385, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D724-0385 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D724-0385
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D724-0385
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D724-0385 available by request