D725-0126 Screening compound: N-(5-{3-ethyl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl}-2-methylphenyl)pyridine-3-carboxamide

D725-0126 Screening compound: N-(5-{3-ethyl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl}-2-methylphenyl)pyridine-3-carboxamide
D725-0126 Screening compound: N-(5-{3-ethyl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl}-2-methylphenyl)pyridine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound D725-0126
N-(5-{3-ethyl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl}-2-methylphenyl)pyridine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D725-0126

Molecular Formula

C18H16N6OS (C18 H16 N6 OS)

Compound Name

N-(5-{3-ethyl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl}-2-methylphenyl)pyridine-3-carboxamide

IUPAC name

N-(5-{3-ethyl-[124]triazolo[34-b][134]thiadiazol-6-yl}-2-methylphenyl)pyridine-3-carboxamide

SMILES

CCc1nnc2sc(-c3cc(NC(c4cnccc4)=O)c(C)cc3)nn12

InChI

InChI=1S/C18H16N6OS/c1-3-15-21-22-18-24(15)23-17(26-18)12-7-6-11(2)14(9-12)20-16(25)13-5-4-8-19-10-13/h4-10H,3H2,1-2H3,(H,20,25)

InChI Key

BQGOWFZDZFVJPN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD08069946

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

364.43

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.208

Distribution Coefficient, logD

2.208

Water Solubility, LogSw

-2.41

Polar Surface Area

66.881

Acid Dissociation Constant (pKa)

11.11

Base Dissociation Constant (pKb)

2.81

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

D725-0126 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with D725-0126 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D725-0126?
Check Price and Availability of D725-0126, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D725-0126 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D725-0126
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D725-0126
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D725-0126 available by request