D727-0521 Screening compound: 2-{6-[(2,6-dimethylphenoxy)methyl]-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-3-yl}pyridine

D727-0521 Screening compound: 2-{6-[(2,6-dimethylphenoxy)methyl]-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-3-yl}pyridine
D727-0521 Screening compound: 2-{6-[(2,6-dimethylphenoxy)methyl]-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-3-yl}pyridine alternative view

Chemical Structure Depiction of ChemDiv screening compound D727-0521
2-{6-[(2,6-dimethylphenoxy)methyl]-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-3-yl}pyridine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D727-0521

Molecular Formula

C17H15N5OS (C17 H15 N5 OS)

Compound Name

2-{6-[(2,6-dimethylphenoxy)methyl]-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-3-yl}pyridine

IUPAC name

2-{6-[(26-dimethylphenoxy)methyl]-[124]triazolo[34-b][134]thiadiazol-3-yl}pyridine

SMILES

Cc1cccc(C)c1OCc(s1)nn2c1nnc2-c1ncccc1

InChI

InChI=1S/C17H15N5OS/c1-11-6-5-7-12(2)15(11)23-10-14-21-22-16(19-20-17(22)24-14)13-8-3-4-9-18-13/h3-9H,10H2,1-2H3

InChI Key

GLIBTJZRZYNROH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD09184755

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

337.41

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.159

Distribution Coefficient, logD

3.157

Water Solubility, LogSw

-2.96

Polar Surface Area

50.937

Acid Dissociation Constant (pKa)

28.80

Base Dissociation Constant (pKb)

5.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.60

D727-0521 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Indoleamine 2,3-dioxygenase 1 Focused Library (5816 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
  • Cancer
  • Digestive system
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Immune system
Targets:
  • Kinases
  • Others

References: we are preparing a list of scientific research reports with D727-0521 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D727-0521?
Check Price and Availability of D727-0521, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D727-0521 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D727-0521
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D727-0521
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D727-0521 available by request