D730-0141 Screening compound: 5-[3-methoxy-4-(prop-2-en-1-yloxy)phenyl]-2-phenyl-3H,4H,5H,6H,7H,8H-pyrido[2,3-d]pyrimidine-4,7-dione

D730-0141 Screening compound: 5-[3-methoxy-4-(prop-2-en-1-yloxy)phenyl]-2-phenyl-3H,4H,5H,6H,7H,8H-pyrido[2,3-d]pyrimidine-4,7-dione
D730-0141 Screening compound: 5-[3-methoxy-4-(prop-2-en-1-yloxy)phenyl]-2-phenyl-3H,4H,5H,6H,7H,8H-pyrido[2,3-d]pyrimidine-4,7-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound D730-0141
5-[3-methoxy-4-(prop-2-en-1-yloxy)phenyl]-2-phenyl-3H,4H,5H,6H,7H,8H-pyrido[2,3-d]pyrimidine-4,7-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D730-0141

Molecular Formula

C23H21N3O4 (C23 H21 N3 O4)

Compound Name

5-[3-methoxy-4-(prop-2-en-1-yloxy)phenyl]-2-phenyl-3H,4H,5H,6H,7H,8H-pyrido[2,3-d]pyrimidine-4,7-dione

IUPAC name

5-[3-methoxy-4-(prop-2-en-1-yloxy)phenyl]-2-phenyl-3H4H5H6H7H8H-pyrido[23-d]pyrimidine-47-dione

SMILES

COc(cc(C(CC(N1)=O)C2=C1N=C(c1ccccc1)NC2=O)cc1)c1OCC=C

InChI

InChI=1S/C23H21N3O4/c1-3-11-30-17-10-9-15(12-18(17)29-2)16-13-19(27)24-22-20(16)23(28)26-21(25-22)14-7-5-4-6-8-14/h3-10,12,16H,1,11,13H2,2H3,(H2,24,25,26,27,28)/t16-/m0/s1

InChI Key

IXOADLRRXGZYEG-INIZCTEOSA-N

MDL Number (MFCD)

MFCD08286792

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

403.44

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.420

Distribution Coefficient, logD

2.410

Water Solubility, LogSw

-3.14

Polar Surface Area

73.393

Acid Dissociation Constant (pKa)

6.73

Base Dissociation Constant (pKb)

4.70

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

17.40

D730-0141 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with D730-0141 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D730-0141?
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What is the minimum amount of D730-0141 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D730-0141
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D730-0141
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D730-0141 available by request