D730-0147 Screening compound: 5-(naphthalen-1-yl)-2-phenyl-3H,4H,5H,6H,7H,8H-pyrido[2,3-d]pyrimidine-4,7-dione

D730-0147 Screening compound: 5-(naphthalen-1-yl)-2-phenyl-3H,4H,5H,6H,7H,8H-pyrido[2,3-d]pyrimidine-4,7-dione
D730-0147 Screening compound: 5-(naphthalen-1-yl)-2-phenyl-3H,4H,5H,6H,7H,8H-pyrido[2,3-d]pyrimidine-4,7-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound D730-0147
5-(naphthalen-1-yl)-2-phenyl-3H,4H,5H,6H,7H,8H-pyrido[2,3-d]pyrimidine-4,7-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

D730-0147

Molecular Formula

C23H17N3O2 (C23 H17 N3 O2)

Compound Name

5-(naphthalen-1-yl)-2-phenyl-3H,4H,5H,6H,7H,8H-pyrido[2,3-d]pyrimidine-4,7-dione

IUPAC name

5-(naphthalen-1-yl)-2-phenyl-3H4H5H6H7H8H-pyrido[23-d]pyrimidine-47-dione

SMILES

O=C(CC1c2cccc3ccccc23)NC(N=C(c2ccccc2)N2)=C1C2=O

InChI

InChI=1S/C23H17N3O2/c27-19-13-18(17-12-6-10-14-7-4-5-11-16(14)17)20-22(24-19)25-21(26-23(20)28)15-8-2-1-3-9-15/h1-12,18H,13H2,(H2,24,25,26,27,28)/t18-/m0/s1

InChI Key

ANBLLHDYTCHWKS-SFHVURJKSA-N

MDL Number (MFCD)

MFCD08285630

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

367.41

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.141

Distribution Coefficient, logD

3.130

Water Solubility, LogSw

-3.32

Polar Surface Area

57.987

Acid Dissociation Constant (pKa)

9.12

Base Dissociation Constant (pKb)

5.15

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

8.70

D730-0147 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with D730-0147 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound D730-0147?
Check Price and Availability of D730-0147, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of D730-0147 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for D730-0147
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for D730-0147
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of D730-0147 available by request