E002-1145 Screening compound: 5-(5-methyl-1H-indazol-1-yl)-5-oxo-N-[3-(propan-2-yloxy)propyl]pentanamide

E002-1145 Screening compound: 5-(5-methyl-1H-indazol-1-yl)-5-oxo-N-[3-(propan-2-yloxy)propyl]pentanamide
E002-1145 Screening compound: 5-(5-methyl-1H-indazol-1-yl)-5-oxo-N-[3-(propan-2-yloxy)propyl]pentanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E002-1145
5-(5-methyl-1H-indazol-1-yl)-5-oxo-N-[3-(propan-2-yloxy)propyl]pentanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E002-1145

Molecular Formula

C19H27N3O3 (C19 H27 N3 O3)

Compound Name

5-(5-methyl-1H-indazol-1-yl)-5-oxo-N-[3-(propan-2-yloxy)propyl]pentanamide

IUPAC name

5-(5-methyl-1H-indazol-1-yl)-5-oxo-N-[3-(propan-2-yloxy)propyl]pentanamide

SMILES

CC(C)OCCCNC(CCCC(n1ncc2c1ccc(C)c2)=O)=O

InChI

InChI=1S/C19H27N3O3/c1-14(2)25-11-5-10-20-18(23)6-4-7-19(24)22-17-9-8-15(3)12-16(17)13-21-22/h8-9,12-14H,4-7,10-11H2,1-3H3,(H,20,23)

InChI Key

GTBSWJBWTGABKQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14835053

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

345.44

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

1.745

Distribution Coefficient, logD

1.745

Water Solubility, LogSw

-2.25

Polar Surface Area

58.261

Acid Dissociation Constant (pKa)

14.07

Base Dissociation Constant (pKb)

4.59

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

52.60

E002-1145 in Drug Discovery

Included in Screening Libraries

Glucocorticoid receptors Library (4806 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
Targets:
  • Nuclear receptors
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E002-1145 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E002-1145?
Check Price and Availability of E002-1145, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E002-1145 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E002-1145
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E002-1145
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E002-1145 available by request