E014-0225 Screening compound: N-[3-(dipropylamino)propyl]-4,6-dimethyl-3-(1H-pyrrol-1-yl)thieno[2,3-b]pyridine-2-carboxamide

E014-0225 Screening compound: N-[3-(dipropylamino)propyl]-4,6-dimethyl-3-(1H-pyrrol-1-yl)thieno[2,3-b]pyridine-2-carboxamide
E014-0225 Screening compound: N-[3-(dipropylamino)propyl]-4,6-dimethyl-3-(1H-pyrrol-1-yl)thieno[2,3-b]pyridine-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E014-0225
N-[3-(dipropylamino)propyl]-4,6-dimethyl-3-(1H-pyrrol-1-yl)thieno[2,3-b]pyridine-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E014-0225

Molecular Formula

C23H32N4OS (C23 H32 N4 OS)

Compound Name

N-[3-(dipropylamino)propyl]-4,6-dimethyl-3-(1H-pyrrol-1-yl)thieno[2,3-b]pyridine-2-carboxamide

IUPAC name

N-[3-(dipropylamino)propyl]-46-dimethyl-3-(1H-pyrrol-1-yl)thieno[23-b]pyridine-2-carboxamide

SMILES

CCCN(CCC)CCCNC(c(sc1nc(C)cc(C)c11)c1-n1cccc1)=O

InChI

InChI=1S/C23H32N4OS/c1-5-11-26(12-6-2)13-9-10-24-22(28)21-20(27-14-7-8-15-27)19-17(3)16-18(4)25-23(19)29-21/h7-8,14-16H,5-6,9-13H2,1-4H3,(H,24,28)

InChI Key

QINOJMORABVNBS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14838041

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

412.6

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.747

Distribution Coefficient, logD

1.989

Water Solubility, LogSw

-4.65

Polar Surface Area

41.594

Acid Dissociation Constant (pKa)

16.45

Base Dissociation Constant (pKb)

10.16

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

47.80

E014-0225 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with E014-0225 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E014-0225?
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What is the minimum amount of E014-0225 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E014-0225
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E014-0225
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E014-0225 available by request