E016-0184 Screening compound: 2-[2-(4-methoxyphenyl)-4-oxo-4H,5H-pyrazolo[1,5-d][1,2,4]triazin-5-yl]-N-[2-(morpholin-4-yl)ethyl]acetamide

E016-0184 Screening compound: 2-[2-(4-methoxyphenyl)-4-oxo-4H,5H-pyrazolo[1,5-d][1,2,4]triazin-5-yl]-N-[2-(morpholin-4-yl)ethyl]acetamide
E016-0184 Screening compound: 2-[2-(4-methoxyphenyl)-4-oxo-4H,5H-pyrazolo[1,5-d][1,2,4]triazin-5-yl]-N-[2-(morpholin-4-yl)ethyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E016-0184
2-[2-(4-methoxyphenyl)-4-oxo-4H,5H-pyrazolo[1,5-d][1,2,4]triazin-5-yl]-N-[2-(morpholin-4-yl)ethyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E016-0184

Molecular Formula

C20H24N6O4 (C20 H24 N6 O4)

Compound Name

2-[2-(4-methoxyphenyl)-4-oxo-4H,5H-pyrazolo[1,5-d][1,2,4]triazin-5-yl]-N-[2-(morpholin-4-yl)ethyl]acetamide

IUPAC name

2-[2-(4-methoxyphenyl)-4-oxo-4H5H-pyrazolo[15-d][124]triazin-5-yl]-N-[2-(morpholin-4-yl)ethyl]acetamide

SMILES

COc(cc1)ccc1-c1nn(C=NN(CC(NCCN2CCOCC2)=O)C2=O)c2c1

InChI

InChI=1S/C20H24N6O4/c1-29-16-4-2-15(3-5-16)17-12-18-20(28)25(22-14-26(18)23-17)13-19(27)21-6-7-24-8-10-30-11-9-24/h2-5,12,14H,6-11,13H2,1H3,(H,21,27)

InChI Key

WFQGXOQQRIRPJC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14838565

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

412.45

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

-0.014

Distribution Coefficient, logD

-0.062

Water Solubility, LogSw

-2.05

Polar Surface Area

85.893

Acid Dissociation Constant (pKa)

14.29

Base Dissociation Constant (pKb)

6.46

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

E016-0184 in Drug Discovery

Included in Screening Libraries

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with E016-0184 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E016-0184?
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What is the minimum amount of E016-0184 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E016-0184
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E016-0184
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E016-0184 available by request