E016-0582 Screening compound: ethyl 1-{2-[2-(furan-2-yl)-4-oxo-4H,5H-pyrazolo[1,5-d][1,2,4]triazin-5-yl]acetyl}piperidine-4-carboxylate

E016-0582 Screening compound: ethyl 1-{2-[2-(furan-2-yl)-4-oxo-4H,5H-pyrazolo[1,5-d][1,2,4]triazin-5-yl]acetyl}piperidine-4-carboxylate
E016-0582 Screening compound: ethyl 1-{2-[2-(furan-2-yl)-4-oxo-4H,5H-pyrazolo[1,5-d][1,2,4]triazin-5-yl]acetyl}piperidine-4-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound E016-0582
ethyl 1-{2-[2-(furan-2-yl)-4-oxo-4H,5H-pyrazolo[1,5-d][1,2,4]triazin-5-yl]acetyl}piperidine-4-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E016-0582

Molecular Formula

C19H21N5O5 (C19 H21 N5 O5)

Compound Name

ethyl 1-{2-[2-(furan-2-yl)-4-oxo-4H,5H-pyrazolo[1,5-d][1,2,4]triazin-5-yl]acetyl}piperidine-4-carboxylate

IUPAC name

ethyl 1-{2-[2-(furan-2-yl)-4-oxo-4H5H-pyrazolo[15-d][124]triazin-5-yl]acetyl}piperidine-4-carboxylate

SMILES

CCOC(C(CC1)CCN1C(CN(C(c1c2)=O)N=Cn1nc2-c1ccco1)=O)=O

InChI

InChI=1S/C19H21N5O5/c1-2-28-19(27)13-5-7-22(8-6-13)17(25)11-23-18(26)15-10-14(16-4-3-9-29-16)21-24(15)12-20-23/h3-4,9-10,12-13H,2,5-8,11H2,1H3

InChI Key

KKHZZLAGGGEEHP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14838680

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

399.41

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

0.300

Distribution Coefficient, logD

0.300

Water Solubility, LogSw

-1.41

Polar Surface Area

87.870

Acid Dissociation Constant (pKa)

17.24

Base Dissociation Constant (pKb)

0.59

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.10

E016-0582 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with E016-0582 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E016-0582?
Check Price and Availability of E016-0582, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E016-0582 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E016-0582
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E016-0582
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E016-0582 available by request