E018-0350 Screening compound: N-[(3-chlorophenyl)methyl]-3-[(4-methylphenyl)sulfanyl]-1H-indole-2-carboxamide

E018-0350 Screening compound: N-[(3-chlorophenyl)methyl]-3-[(4-methylphenyl)sulfanyl]-1H-indole-2-carboxamide
E018-0350 Screening compound: N-[(3-chlorophenyl)methyl]-3-[(4-methylphenyl)sulfanyl]-1H-indole-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E018-0350
N-[(3-chlorophenyl)methyl]-3-[(4-methylphenyl)sulfanyl]-1H-indole-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E018-0350

Molecular Formula

C23H19ClN2OS (C23 H19 ClN2 OS)

Compound Name

N-[(3-chlorophenyl)methyl]-3-[(4-methylphenyl)sulfanyl]-1H-indole-2-carboxamide

IUPAC name

N-[(3-chlorophenyl)methyl]-3-[(4-methylphenyl)sulfanyl]-1H-indole-2-carboxamide

SMILES

Cc(cc1)ccc1Sc1c(C(NCc2cccc(Cl)c2)=O)[nH]c2c1cccc2

InChI

InChI=1S/C23H19ClN2OS/c1-15-9-11-18(12-10-15)28-22-19-7-2-3-8-20(19)26-21(22)23(27)25-14-16-5-4-6-17(24)13-16/h2-13,26H,14H2,1H3,(H,25,27)

InChI Key

ZWRWOVQLVHUJMW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14839159

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

406.94

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

5.964

Distribution Coefficient, logD

5.964

Water Solubility, LogSw

-6.16

Polar Surface Area

34.500

Acid Dissociation Constant (pKa)

13.37

Base Dissociation Constant (pKb)

-3.56

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

8.70

E018-0350 in Drug Discovery

Included in Screening Libraries

Anti-infective Library (19449 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with E018-0350 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E018-0350?
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What is the minimum amount of E018-0350 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E018-0350
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E018-0350
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E018-0350 available by request