E018-0435 Screening compound: 3-[(4-methylphenyl)sulfanyl]-N-(2-phenylethyl)-1H-indole-2-carboxamide

E018-0435 Screening compound: 3-[(4-methylphenyl)sulfanyl]-N-(2-phenylethyl)-1H-indole-2-carboxamide
E018-0435 Screening compound: 3-[(4-methylphenyl)sulfanyl]-N-(2-phenylethyl)-1H-indole-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E018-0435
3-[(4-methylphenyl)sulfanyl]-N-(2-phenylethyl)-1H-indole-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E018-0435

Molecular Formula

C24H22N2OS (C24 H22 N2 OS)

Compound Name

3-[(4-methylphenyl)sulfanyl]-N-(2-phenylethyl)-1H-indole-2-carboxamide

IUPAC name

3-[(4-methylphenyl)sulfanyl]-N-(2-phenylethyl)-1H-indole-2-carboxamide

SMILES

Cc(cc1)ccc1Sc1c(C(NCCc2ccccc2)=O)[nH]c2c1cccc2

InChI

InChI=1S/C24H22N2OS/c1-17-11-13-19(14-12-17)28-23-20-9-5-6-10-21(20)26-22(23)24(27)25-16-15-18-7-3-2-4-8-18/h2-14,26H,15-16H2,1H3,(H,25,27)

InChI Key

RKBCOFXIFWCAQY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14839173

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

386.52

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

5.200

Distribution Coefficient, logD

5.200

Water Solubility, LogSw

-5.30

Polar Surface Area

34.341

Acid Dissociation Constant (pKa)

14.74

Base Dissociation Constant (pKb)

-2.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.50

E018-0435 in Drug Discovery

Included in Screening Libraries

Cardiovascular Library (22201 compounds)

MCL1 Targeted Library (12200 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cardiovascular
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with E018-0435 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E018-0435?
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What is the minimum amount of E018-0435 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E018-0435
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E018-0435
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E018-0435 available by request