E018-1089 Screening compound: 3-[(4-chlorophenyl)sulfanyl]-6-methyl-N-[2-(2-methylpiperidin-1-yl)ethyl]-1H-indole-2-carboxamide

E018-1089 Screening compound: 3-[(4-chlorophenyl)sulfanyl]-6-methyl-N-[2-(2-methylpiperidin-1-yl)ethyl]-1H-indole-2-carboxamide
E018-1089 Screening compound: 3-[(4-chlorophenyl)sulfanyl]-6-methyl-N-[2-(2-methylpiperidin-1-yl)ethyl]-1H-indole-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E018-1089
3-[(4-chlorophenyl)sulfanyl]-6-methyl-N-[2-(2-methylpiperidin-1-yl)ethyl]-1H-indole-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E018-1089

Molecular Formula

C24H28ClN3OS (C24 H28 ClN3 OS)

Compound Name

3-[(4-chlorophenyl)sulfanyl]-6-methyl-N-[2-(2-methylpiperidin-1-yl)ethyl]-1H-indole-2-carboxamide

IUPAC name

3-[(4-chlorophenyl)sulfanyl]-6-methyl-N-[2-(2-methylpiperidin-1-yl)ethyl]-1H-indole-2-carboxamide

SMILES

CC1N(CCNC(c([nH]c2c3ccc(C)c2)c3Sc(cc2)ccc2Cl)=O)CCCC1

InChI

InChI=1S/C24H28ClN3OS/c1-16-6-11-20-21(15-16)27-22(23(20)30-19-9-7-18(25)8-10-19)24(29)26-12-14-28-13-4-3-5-17(28)2/h6-11,15,17,27H,3-5,12-14H2,1-2H3,(H,26,29)/t17-/m0/s1

InChI Key

WJEVSNKSXSTWMO-KRWDZBQOSA-N

MDL Number (MFCD)

MFCD14839296

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

442.02

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.287

Distribution Coefficient, logD

3.734

Water Solubility, LogSw

-5.89

Polar Surface Area

37.774

Acid Dissociation Constant (pKa)

14.16

Base Dissociation Constant (pKb)

8.94

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

37.50

E018-1089 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Nervous system
  • Cardiovascular
Targets:
  • GPCR
  • Others
  • Ion Channels
Mechanism of action:
  • Receptor's ligands
  • Epigenetic

References: we are preparing a list of scientific research reports with E018-1089 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E018-1089?
Check Price and Availability of E018-1089, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E018-1089 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E018-1089
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E018-1089
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E018-1089 available by request