E018-2263 Screening compound: N-[(3-fluorophenyl)methyl]-6-methoxy-3-[(4-methylphenyl)sulfanyl]-1H-indole-2-carboxamide

E018-2263 Screening compound: N-[(3-fluorophenyl)methyl]-6-methoxy-3-[(4-methylphenyl)sulfanyl]-1H-indole-2-carboxamide
E018-2263 Screening compound: N-[(3-fluorophenyl)methyl]-6-methoxy-3-[(4-methylphenyl)sulfanyl]-1H-indole-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E018-2263
N-[(3-fluorophenyl)methyl]-6-methoxy-3-[(4-methylphenyl)sulfanyl]-1H-indole-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E018-2263

Molecular Formula

C24H21FN2O2S (C24 H21 FN2 O2 S)

Compound Name

N-[(3-fluorophenyl)methyl]-6-methoxy-3-[(4-methylphenyl)sulfanyl]-1H-indole-2-carboxamide

IUPAC name

N-[(3-fluorophenyl)methyl]-6-methoxy-3-[(4-methylphenyl)sulfanyl]-1H-indole-2-carboxamide

SMILES

Cc(cc1)ccc1Sc1c(C(NCc2cc(F)ccc2)=O)[nH]c2c1ccc(OC)c2

InChI

InChI=1S/C24H21FN2O2S/c1-15-6-9-19(10-7-15)30-23-20-11-8-18(29-2)13-21(20)27-22(23)24(28)26-14-16-4-3-5-17(25)12-16/h3-13,27H,14H2,1-2H3,(H,26,28)

InChI Key

GUWXIWPMZXISOF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14839448

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

420.51

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.698

Distribution Coefficient, logD

5.698

Water Solubility, LogSw

-5.58

Polar Surface Area

42.044

Acid Dissociation Constant (pKa)

13.37

Base Dissociation Constant (pKb)

-3.56

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.50

E018-2263 in Drug Discovery

Included in Screening Libraries

Anti-infective Library (19449 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with E018-2263 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E018-2263?
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What is the minimum amount of E018-2263 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E018-2263
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E018-2263
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E018-2263 available by request