E018-2376 Screening compound: 3-[(4-chlorophenyl)sulfanyl]-6-methoxy-N-[3-(morpholin-4-yl)propyl]-1H-indole-2-carboxamide

E018-2376 Screening compound: 3-[(4-chlorophenyl)sulfanyl]-6-methoxy-N-[3-(morpholin-4-yl)propyl]-1H-indole-2-carboxamide
E018-2376 Screening compound: 3-[(4-chlorophenyl)sulfanyl]-6-methoxy-N-[3-(morpholin-4-yl)propyl]-1H-indole-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E018-2376
3-[(4-chlorophenyl)sulfanyl]-6-methoxy-N-[3-(morpholin-4-yl)propyl]-1H-indole-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E018-2376

Molecular Formula

C23H26ClN3O3S (C23 H26 ClN3 O3 S)

Compound Name

3-[(4-chlorophenyl)sulfanyl]-6-methoxy-N-[3-(morpholin-4-yl)propyl]-1H-indole-2-carboxamide

IUPAC name

3-[(4-chlorophenyl)sulfanyl]-6-methoxy-N-[3-(morpholin-4-yl)propyl]-1H-indole-2-carboxamide

SMILES

COc(cc1)cc2c1c(Sc(cc1)ccc1Cl)c(C(NCCCN1CCOCC1)=O)[nH]2

InChI

InChI=1S/C23H26ClN3O3S/c1-29-17-5-8-19-20(15-17)26-21(22(19)31-18-6-3-16(24)4-7-18)23(28)25-9-2-10-27-11-13-30-14-12-27/h3-8,15,26H,2,9-14H2,1H3,(H,25,28)

InChI Key

QLNXPBJODJECRD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14839468

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

460

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.900

Distribution Coefficient, logD

3.512

Water Solubility, LogSw

-4.53

Polar Surface Area

53.776

Acid Dissociation Constant (pKa)

15.88

Base Dissociation Constant (pKb)

7.56

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.80

E018-2376 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Histone Deacetylases (HDAC) Targeted Library (9760 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Endocrine
  • Immune system
Targets:
  • Others
Mechanism of action:
  • Epigenetic
  • Epigenetic

References: we are preparing a list of scientific research reports with E018-2376 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E018-2376?
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What is the minimum amount of E018-2376 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E018-2376
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E018-2376
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E018-2376 available by request