E130-0192 Screening compound: N-(5-chloropyridin-2-yl)-3-[3-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1,2,4-oxadiazol-5-yl]propanamide

E130-0192 Screening compound: N-(5-chloropyridin-2-yl)-3-[3-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1,2,4-oxadiazol-5-yl]propanamide
E130-0192 Screening compound: N-(5-chloropyridin-2-yl)-3-[3-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1,2,4-oxadiazol-5-yl]propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E130-0192
N-(5-chloropyridin-2-yl)-3-[3-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1,2,4-oxadiazol-5-yl]propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E130-0192

Molecular Formula

C16H18ClN5O2 (C16 H18 ClN5 O2)

Compound Name

N-(5-chloropyridin-2-yl)-3-[3-(1-methyl-1,2,3,6-tetrahydropyridin-4-yl)-1,2,4-oxadiazol-5-yl]propanamide

IUPAC name

N-(5-chloropyridin-2-yl)-3-[3-(1-methyl-1236-tetrahydropyridin-4-yl)-124-oxadiazol-5-yl]propanamide

SMILES

CN(CC1)CC=C1c1noc(CCC(Nc(cc2)ncc2Cl)=O)n1

InChI

InChI=1S/C16H18ClN5O2/c1-22-8-6-11(7-9-22)16-20-15(24-21-16)5-4-14(23)19-13-3-2-12(17)10-18-13/h2-3,6,10H,4-5,7-9H2,1H3,(H,18,19,23)

InChI Key

LRZGGLLRTIHXHB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14840764

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

347.8

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.598

Distribution Coefficient, logD

2.191

Water Solubility, LogSw

-3.30

Polar Surface Area

67.833

Acid Dissociation Constant (pKa)

8.81

Base Dissociation Constant (pKb)

7.59

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

37.50

E130-0192 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Others
  • Kinases
Mechanism of action:
  • Epigenetic
Agro:
  • Agro

References: we are preparing a list of scientific research reports with E130-0192 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E130-0192?
Check Price and Availability of E130-0192, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E130-0192 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E130-0192
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E130-0192
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E130-0192 available by request