E130-0855 Screening compound: N,4-bis(4-fluorophenyl)-5H-chromeno[4,3-d]pyrimidin-2-amine

E130-0855 Screening compound: N,4-bis(4-fluorophenyl)-5H-chromeno[4,3-d]pyrimidin-2-amine
E130-0855 Screening compound: N,4-bis(4-fluorophenyl)-5H-chromeno[4,3-d]pyrimidin-2-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound E130-0855
N,4-bis(4-fluorophenyl)-5H-chromeno[4,3-d]pyrimidin-2-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E130-0855

Molecular Formula

C23H15F2N3O (C23 H15 F2 N3 O)

Compound Name

N,4-bis(4-fluorophenyl)-5H-chromeno[4,3-d]pyrimidin-2-amine

IUPAC name

N4-bis(4-fluorophenyl)-5H-chromeno[43-d]pyrimidin-2-amine

SMILES

Fc(cc1)ccc1-c1nc(Nc(cc2)ccc2F)nc-2c1COc1c2cccc1

InChI

InChI=1S/C23H15F2N3O/c24-15-7-5-14(6-8-15)21-19-13-29-20-4-2-1-3-18(20)22(19)28-23(27-21)26-17-11-9-16(25)10-12-17/h1-12H,13H2,(H,26,27,28)

InChI Key

HULFGNDEMYMEME-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14840827

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

387.39

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.858

Distribution Coefficient, logD

5.858

Water Solubility, LogSw

-6.09

Polar Surface Area

38.315

Acid Dissociation Constant (pKa)

17.07

Base Dissociation Constant (pKb)

3.39

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.30

E130-0855 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

3D-Pharmacophore Based Diversity Library (49813 compounds)

Anti-Aging Library (44940 compounds)

Therapeutical Diversity Annotated Library (7563 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with E130-0855 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E130-0855?
Check Price and Availability of E130-0855, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E130-0855 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E130-0855
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E130-0855
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E130-0855 available by request