E136-0016 Screening compound: 2-(1H-indol-3-yl)-N-(5-methyl-1,3,4-thiadiazol-2-yl)-2-oxoacetamide

E136-0016 Screening compound: 2-(1H-indol-3-yl)-N-(5-methyl-1,3,4-thiadiazol-2-yl)-2-oxoacetamide
E136-0016 Screening compound: 2-(1H-indol-3-yl)-N-(5-methyl-1,3,4-thiadiazol-2-yl)-2-oxoacetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E136-0016
2-(1H-indol-3-yl)-N-(5-methyl-1,3,4-thiadiazol-2-yl)-2-oxoacetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E136-0016

Molecular Formula

C13H10N4O2S (C13 H10 N4 O2 S)

Compound Name

2-(1H-indol-3-yl)-N-(5-methyl-1,3,4-thiadiazol-2-yl)-2-oxoacetamide

IUPAC name

2-(1H-indol-3-yl)-N-(5-methyl-134-thiadiazol-2-yl)-2-oxoacetamide

SMILES

Cc1nnc(NC(C(c2c[nH]c3c2cccc3)=O)=O)s1

InChI

InChI=1S/C13H10N4O2S/c1-7-16-17-13(20-7)15-12(19)11(18)9-6-14-10-5-3-2-4-8(9)10/h2-6,14H,1H3,(H,15,17,19)

InChI Key

UIYZAEUNVYWGSE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14841107

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

286.31

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.229

Distribution Coefficient, logD

0.797

Water Solubility, LogSw

-3.03

Polar Surface Area

70.290

Acid Dissociation Constant (pKa)

5.98

Base Dissociation Constant (pKb)

-1.53

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

7.70

E136-0016 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Covalent Inhibitors Library (7986 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Structure:
  • Cyclic compounds
  • 3D
  • Fragments
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with E136-0016 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E136-0016?
Check Price and Availability of E136-0016, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E136-0016 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E136-0016
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E136-0016
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E136-0016 available by request