E136-0873 Screening compound: N-(4-ethoxyphenyl)-1,3-diphenyl-1H-pyrazole-4-carboxamide

E136-0873 Screening compound: N-(4-ethoxyphenyl)-1,3-diphenyl-1H-pyrazole-4-carboxamide
E136-0873 Screening compound: N-(4-ethoxyphenyl)-1,3-diphenyl-1H-pyrazole-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E136-0873
N-(4-ethoxyphenyl)-1,3-diphenyl-1H-pyrazole-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E136-0873

Molecular Formula

C24H21N3O2 (C24 H21 N3 O2)

Compound Name

N-(4-ethoxyphenyl)-1,3-diphenyl-1H-pyrazole-4-carboxamide

IUPAC name

N-(4-ethoxyphenyl)-13-diphenyl-1H-pyrazole-4-carboxamide

SMILES

CCOc(cc1)ccc1NC(c1cn(-c2ccccc2)nc1-c1ccccc1)=O

InChI

InChI=1S/C24H21N3O2/c1-2-29-21-15-13-19(14-16-21)25-24(28)22-17-27(20-11-7-4-8-12-20)26-23(22)18-9-5-3-6-10-18/h3-17H,2H2,1H3,(H,25,28)

InChI Key

SHBIAEMDLKCTJP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14841260

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

383.45

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.869

Distribution Coefficient, logD

4.869

Water Solubility, LogSw

-4.38

Polar Surface Area

45.086

Acid Dissociation Constant (pKa)

12.66

Base Dissociation Constant (pKb)

-2.21

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

8.30

E136-0873 in Drug Discovery

Included in Screening Libraries

Human Kinases Annotated Library (2415 compounds)

Selective Target Activity Profiling Library (14702 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Proteases
  • Kinases

References: we are preparing a list of scientific research reports with E136-0873 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E136-0873?
Check Price and Availability of E136-0873, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E136-0873 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E136-0873
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E136-0873
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E136-0873 available by request