E136-1056 Screening compound: 3-(4-chlorophenyl)-N-(5-methyl-1,3-thiazol-2-yl)-1-phenyl-1H-pyrazole-4-carboxamide

E136-1056 Screening compound: 3-(4-chlorophenyl)-N-(5-methyl-1,3-thiazol-2-yl)-1-phenyl-1H-pyrazole-4-carboxamide
E136-1056 Screening compound: 3-(4-chlorophenyl)-N-(5-methyl-1,3-thiazol-2-yl)-1-phenyl-1H-pyrazole-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E136-1056
3-(4-chlorophenyl)-N-(5-methyl-1,3-thiazol-2-yl)-1-phenyl-1H-pyrazole-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E136-1056

Molecular Formula

C20H15ClN4OS (C20 H15 ClN4 OS)

Compound Name

3-(4-chlorophenyl)-N-(5-methyl-1,3-thiazol-2-yl)-1-phenyl-1H-pyrazole-4-carboxamide

IUPAC name

3-(4-chlorophenyl)-N-(5-methyl-13-thiazol-2-yl)-1-phenyl-1H-pyrazole-4-carboxamide

SMILES

Cc1cnc(NC(c2cn(-c3ccccc3)nc2-c(cc2)ccc2Cl)=O)s1

InChI

InChI=1S/C20H15ClN4OS/c1-13-11-22-20(27-13)23-19(26)17-12-25(16-5-3-2-4-6-16)24-18(17)14-7-9-15(21)10-8-14/h2-12H,1H3,(H,22,23,26)

InChI Key

BKEKJZYRNZYXGG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14841279

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

394.88

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.389

Distribution Coefficient, logD

5.385

Water Solubility, LogSw

-5.93

Polar Surface Area

48.530

Acid Dissociation Constant (pKa)

9.43

Base Dissociation Constant (pKb)

2.46

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.00

E136-1056 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Anti-Aging Library (44940 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases
  • Kinases
  • Kinases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with E136-1056 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E136-1056?
Check Price and Availability of E136-1056, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E136-1056 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E136-1056
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E136-1056
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E136-1056 available by request