E138-2227 Screening compound: 2-amino-5-bromo-N~3~-(4-isopropylphenyl)-N~3~-propyl-3-pyridinesulfonamide

E138-2227 Screening compound: 2-amino-5-bromo-N~3~-(4-isopropylphenyl)-N~3~-propyl-3-pyridinesulfonamide
E138-2227 Screening compound: 2-amino-5-bromo-N~3~-(4-isopropylphenyl)-N~3~-propyl-3-pyridinesulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E138-2227
2-amino-5-bromo-N~3~-(4-isopropylphenyl)-N~3~-propyl-3-pyridinesulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E138-2227

Molecular Formula

C17H22BrN3O2S (C17 H22 BrN3 O2 S)

Compound Name

2-amino-5-bromo-N~3~-(4-isopropylphenyl)-N~3~-propyl-3-pyridinesulfonamide

IUPAC name

n/a

SMILES

CCCN(c1ccc(C(C)C)cc1)S(c1cc(Br)cnc1N)(=O)=O

InChI

InChI=1S/C17H22BrN3O2S/c1-4-9-21(15-7-5-13(6-8-15)12(2)3)24(22,23)16-10-14(18)11-20-17(16)19/h5-8,10-12H,4,9H2,1-3H3,(H2,19,20)

InChI Key

PZHUYYDPHYFQTK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14841716

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

412.35

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.439

Distribution Coefficient, logD

4.439

Water Solubility, LogSw

-4.28

Polar Surface Area

61.876

Acid Dissociation Constant (pKa)

16.98

Base Dissociation Constant (pKb)

-2.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

35.30

E138-2227 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases
  • Kinases
  • Proteases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with E138-2227 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E138-2227?
Check Price and Availability of E138-2227, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E138-2227 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E138-2227
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E138-2227
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E138-2227 available by request