E139-0734 Screening compound: 7-fluoro-2-[4-(prop-2-en-1-yloxy)phenyl]-3H,4H,5H-chromeno[2,3-d]pyrimidin-4-one

E139-0734 Screening compound: 7-fluoro-2-[4-(prop-2-en-1-yloxy)phenyl]-3H,4H,5H-chromeno[2,3-d]pyrimidin-4-one
E139-0734 Screening compound: 7-fluoro-2-[4-(prop-2-en-1-yloxy)phenyl]-3H,4H,5H-chromeno[2,3-d]pyrimidin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound E139-0734
7-fluoro-2-[4-(prop-2-en-1-yloxy)phenyl]-3H,4H,5H-chromeno[2,3-d]pyrimidin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E139-0734

Molecular Formula

C20H15FN2O3 (C20 H15 FN2 O3)

Compound Name

7-fluoro-2-[4-(prop-2-en-1-yloxy)phenyl]-3H,4H,5H-chromeno[2,3-d]pyrimidin-4-one

IUPAC name

7-fluoro-2-[4-(prop-2-en-1-yloxy)phenyl]-3H4H5H-chromeno[23-d]pyrimidin-4-one

SMILES

C=CCOc(cc1)ccc1C(N1)=NC(Oc(cc2)c(C3)cc2F)=C3C1=O

InChI

InChI=1S/C20H15FN2O3/c1-2-9-25-15-6-3-12(4-7-15)18-22-19(24)16-11-13-10-14(21)5-8-17(13)26-20(16)23-18/h2-8,10H,1,9,11H2,(H,22,23,24)

InChI Key

SDKDNAHVQAFXQD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14841899

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

350.35

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.830

Distribution Coefficient, logD

3.744

Water Solubility, LogSw

-4.12

Polar Surface Area

50.135

Acid Dissociation Constant (pKa)

8.06

Base Dissociation Constant (pKb)

4.49

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.00

E139-0734 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Antimitotic Tubulin Library (17355 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with E139-0734 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E139-0734?
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What is the minimum amount of E139-0734 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E139-0734
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E139-0734
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E139-0734 available by request