E141-1029 Screening compound: N-(2,4-difluorophenyl)-1-(2-methoxy-5-methylphenyl)-5-methyl-1H-1,2,3-triazole-4-carboxamide

E141-1029 Screening compound: N-(2,4-difluorophenyl)-1-(2-methoxy-5-methylphenyl)-5-methyl-1H-1,2,3-triazole-4-carboxamide
E141-1029 Screening compound: N-(2,4-difluorophenyl)-1-(2-methoxy-5-methylphenyl)-5-methyl-1H-1,2,3-triazole-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E141-1029
N-(2,4-difluorophenyl)-1-(2-methoxy-5-methylphenyl)-5-methyl-1H-1,2,3-triazole-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E141-1029

Molecular Formula

C18H16F2N4O2 (C18 H16 F2 N4 O2)

Compound Name

N-(2,4-difluorophenyl)-1-(2-methoxy-5-methylphenyl)-5-methyl-1H-1,2,3-triazole-4-carboxamide

IUPAC name

N-(24-difluorophenyl)-1-(2-methoxy-5-methylphenyl)-5-methyl-1H-123-triazole-4-carboxamide

SMILES

Cc1c(C(Nc(ccc(F)c2)c2F)=O)nnn1-c(cc(C)cc1)c1OC

InChI

InChI=1S/C18H16F2N4O2/c1-10-4-7-16(26-3)15(8-10)24-11(2)17(22-23-24)18(25)21-14-6-5-12(19)9-13(14)20/h4-9H,1-3H3,(H,21,25)

InChI Key

MGNDYHOCRIRHJZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14842088

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

358.35

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.245

Distribution Coefficient, logD

3.002

Water Solubility, LogSw

-3.58

Polar Surface Area

56.804

Acid Dissociation Constant (pKa)

7.53

Base Dissociation Constant (pKb)

-0.05

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

E141-1029 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with E141-1029 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E141-1029?
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What is the minimum amount of E141-1029 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E141-1029
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E141-1029
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E141-1029 available by request