E146-0463 Screening compound: ethyl 2-({4H-chromeno[3,4-d][1,2]oxazol-3-yl}formamido)propanoate

E146-0463 Screening compound: ethyl 2-({4H-chromeno[3,4-d][1,2]oxazol-3-yl}formamido)propanoate
E146-0463 Screening compound: ethyl 2-({4H-chromeno[3,4-d][1,2]oxazol-3-yl}formamido)propanoate alternative view

Chemical Structure Depiction of ChemDiv screening compound E146-0463
ethyl 2-({4H-chromeno[3,4-d][1,2]oxazol-3-yl}formamido)propanoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E146-0463

Molecular Formula

C16H16N2O5 (C16 H16 N2 O5)

Compound Name

ethyl 2-({4H-chromeno[3,4-d][1,2]oxazol-3-yl}formamido)propanoate

IUPAC name

ethyl 2-({4H-chromeno[34-d][12]oxazol-3-yl}formamido)propanoate

SMILES

CCOC(C(C)NC(c1noc-2c1COc1c2cccc1)=O)=O

InChI

InChI=1S/C16H16N2O5/c1-3-21-16(20)9(2)17-15(19)13-11-8-22-12-7-5-4-6-10(12)14(11)23-18-13/h4-7,9H,3,8H2,1-2H3,(H,17,19)/t9-/m0/s1

InChI Key

CGNNQCXJSAZNAA-VIFPVBQESA-N

MDL Number (MFCD)

MFCD14842686

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

316.31

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.016

Distribution Coefficient, logD

2.016

Water Solubility, LogSw

-2.66

Polar Surface Area

75.370

Acid Dissociation Constant (pKa)

13.00

Base Dissociation Constant (pKb)

-3.43

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

31.30

E146-0463 in Drug Discovery

Included in Screening Libraries

CNS MPO Library (28609 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with E146-0463 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E146-0463?
Check Price and Availability of E146-0463, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E146-0463 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E146-0463
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E146-0463
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E146-0463 available by request