E146-0788 Screening compound: N-(6-methylpyridin-2-yl)-4H-thiochromeno[3,4-d][1,2]oxazole-3-carboxamide

E146-0788 Screening compound: N-(6-methylpyridin-2-yl)-4H-thiochromeno[3,4-d][1,2]oxazole-3-carboxamide
E146-0788 Screening compound: N-(6-methylpyridin-2-yl)-4H-thiochromeno[3,4-d][1,2]oxazole-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E146-0788
N-(6-methylpyridin-2-yl)-4H-thiochromeno[3,4-d][1,2]oxazole-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E146-0788

Molecular Formula

C17H13N3O2S (C17 H13 N3 O2 S)

Compound Name

N-(6-methylpyridin-2-yl)-4H-thiochromeno[3,4-d][1,2]oxazole-3-carboxamide

IUPAC name

N-(6-methylpyridin-2-yl)-4H-thiochromeno[34-d][12]oxazole-3-carboxamide

SMILES

Cc1cccc(NC(c2noc-3c2CSc2c3cccc2)=O)n1

InChI

InChI=1S/C17H13N3O2S/c1-10-5-4-8-14(18-10)19-17(21)15-12-9-23-13-7-3-2-6-11(13)16(12)22-20-15/h2-8H,9H2,1H3,(H,18,19,21)

InChI Key

XDSFZZKOKUDWPV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14842747

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

323.38

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.706

Distribution Coefficient, logD

3.705

Water Solubility, LogSw

-4.04

Polar Surface Area

54.400

Acid Dissociation Constant (pKa)

10.02

Base Dissociation Constant (pKb)

4.03

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.80

E146-0788 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Nervous system
  • Cardiovascular
Mechanism of action:
  • Epigenetic
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with E146-0788 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E146-0788?
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What is the minimum amount of E146-0788 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E146-0788
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E146-0788
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E146-0788 available by request