E146-1019 Screening compound: 4-phenyl-1-{4H-thiochromeno[3,4-d][1,2]oxazole-3-carbonyl}-1,2,3,6-tetrahydropyridine

E146-1019 Screening compound: 4-phenyl-1-{4H-thiochromeno[3,4-d][1,2]oxazole-3-carbonyl}-1,2,3,6-tetrahydropyridine
E146-1019 Screening compound: 4-phenyl-1-{4H-thiochromeno[3,4-d][1,2]oxazole-3-carbonyl}-1,2,3,6-tetrahydropyridine alternative view

Chemical Structure Depiction of ChemDiv screening compound E146-1019
4-phenyl-1-{4H-thiochromeno[3,4-d][1,2]oxazole-3-carbonyl}-1,2,3,6-tetrahydropyridine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E146-1019

Molecular Formula

C22H18N2O2S (C22 H18 N2 O2 S)

Compound Name

4-phenyl-1-{4H-thiochromeno[3,4-d][1,2]oxazole-3-carbonyl}-1,2,3,6-tetrahydropyridine

IUPAC name

4-phenyl-1-{4H-thiochromeno[34-d][12]oxazole-3-carbonyl}-1236-tetrahydropyridine

SMILES

O=C(c1noc-2c1CSc1c2cccc1)N(CC1)CC=C1c1ccccc1

InChI

InChI=1S/C22H18N2O2S/c25-22(24-12-10-16(11-13-24)15-6-2-1-3-7-15)20-18-14-27-19-9-5-4-8-17(19)21(18)26-23-20/h1-10H,11-14H2

InChI Key

XKWDLOXLRCZYPR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14842859

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

374.46

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.534

Distribution Coefficient, logD

4.534

Water Solubility, LogSw

-4.44

Polar Surface Area

38.696

Acid Dissociation Constant (pKa)

19.32

Base Dissociation Constant (pKb)

-4.95

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.20

E146-1019 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with E146-1019 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E146-1019?
Check Price and Availability of E146-1019, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E146-1019 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E146-1019
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E146-1019
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E146-1019 available by request