E146-1110 Screening compound: 1-methyl-N-[3-(trifluoromethyl)phenyl]-1H,4H-chromeno[4,3-c]pyrazole-3-carboxamide

E146-1110 Screening compound: 1-methyl-N-[3-(trifluoromethyl)phenyl]-1H,4H-chromeno[4,3-c]pyrazole-3-carboxamide
E146-1110 Screening compound: 1-methyl-N-[3-(trifluoromethyl)phenyl]-1H,4H-chromeno[4,3-c]pyrazole-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E146-1110
1-methyl-N-[3-(trifluoromethyl)phenyl]-1H,4H-chromeno[4,3-c]pyrazole-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E146-1110

Molecular Formula

C19H14F3N3O2 (C19 H14 F3 N3 O2)

Compound Name

1-methyl-N-[3-(trifluoromethyl)phenyl]-1H,4H-chromeno[4,3-c]pyrazole-3-carboxamide

IUPAC name

1-methyl-N-[3-(trifluoromethyl)phenyl]-1H4H-chromeno[43-c]pyrazole-3-carboxamide

SMILES

Cn1nc(C(Nc2cccc(C(F)(F)F)c2)=O)c2c1-c(cccc1)c1OC2

InChI

InChI=1S/C19H14F3N3O2/c1-25-17-13-7-2-3-8-15(13)27-10-14(17)16(24-25)18(26)23-12-6-4-5-11(9-12)19(20,21)22/h2-9H,10H2,1H3,(H,23,26)

InChI Key

VXHHQRYFORKPDE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14842893

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

373.33

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.934

Distribution Coefficient, logD

3.929

Water Solubility, LogSw

-4.14

Polar Surface Area

46.102

Acid Dissociation Constant (pKa)

9.38

Base Dissociation Constant (pKb)

-1.56

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

15.80

E146-1110 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Antiviral Library (67538 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Antiviral
  • Infections
  • Immune system

References: we are preparing a list of scientific research reports with E146-1110 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E146-1110?
Check Price and Availability of E146-1110, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E146-1110 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E146-1110
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E146-1110
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E146-1110 available by request