E146-1138 Screening compound: 4-methyl-1-{1-methyl-1H,4H-chromeno[4,3-c]pyrazole-3-carbonyl}piperidine

E146-1138 Screening compound: 4-methyl-1-{1-methyl-1H,4H-chromeno[4,3-c]pyrazole-3-carbonyl}piperidine
E146-1138 Screening compound: 4-methyl-1-{1-methyl-1H,4H-chromeno[4,3-c]pyrazole-3-carbonyl}piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound E146-1138
4-methyl-1-{1-methyl-1H,4H-chromeno[4,3-c]pyrazole-3-carbonyl}piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E146-1138

Molecular Formula

C18H21N3O2 (C18 H21 N3 O2)

Compound Name

4-methyl-1-{1-methyl-1H,4H-chromeno[4,3-c]pyrazole-3-carbonyl}piperidine

IUPAC name

4-methyl-1-{1-methyl-1H4H-chromeno[43-c]pyrazole-3-carbonyl}piperidine

SMILES

CC(CC1)CCN1C(c1nn(C)c-2c1COc1c2cccc1)=O

InChI

InChI=1S/C18H21N3O2/c1-12-7-9-21(10-8-12)18(22)16-14-11-23-15-6-4-3-5-13(15)17(14)20(2)19-16/h3-6,12H,7-11H2,1-2H3

InChI Key

VAVWBNHJICBCBR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14842918

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

311.38

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.372

Distribution Coefficient, logD

2.372

Water Solubility, LogSw

-2.76

Polar Surface Area

39.659

Acid Dissociation Constant (pKa)

19.18

Base Dissociation Constant (pKb)

-1.52

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

44.40

E146-1138 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • Receptor's ligands
  • Epigenetic
Therapeutical areas:
  • Immune system
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic

References: we are preparing a list of scientific research reports with E146-1138 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E146-1138?
Check Price and Availability of E146-1138, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E146-1138 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E146-1138
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E146-1138
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E146-1138 available by request