E146-1163 Screening compound: 1-methyl-N-[(pyridin-2-yl)methyl]-1H,4H-chromeno[4,3-c]pyrazole-3-carboxamide

E146-1163 Screening compound: 1-methyl-N-[(pyridin-2-yl)methyl]-1H,4H-chromeno[4,3-c]pyrazole-3-carboxamide
E146-1163 Screening compound: 1-methyl-N-[(pyridin-2-yl)methyl]-1H,4H-chromeno[4,3-c]pyrazole-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E146-1163
1-methyl-N-[(pyridin-2-yl)methyl]-1H,4H-chromeno[4,3-c]pyrazole-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E146-1163

Molecular Formula

C18H16N4O2 (C18 H16 N4 O2)

Compound Name

1-methyl-N-[(pyridin-2-yl)methyl]-1H,4H-chromeno[4,3-c]pyrazole-3-carboxamide

IUPAC name

1-methyl-N-[(pyridin-2-yl)methyl]-1H4H-chromeno[43-c]pyrazole-3-carboxamide

SMILES

Cn1nc(C(NCc2ncccc2)=O)c2c1-c(cccc1)c1OC2

InChI

InChI=1S/C18H16N4O2/c1-22-17-13-7-2-3-8-15(13)24-11-14(17)16(21-22)18(23)20-10-12-6-4-5-9-19-12/h2-9H,10-11H2,1H3,(H,20,23)

InChI Key

KEDCLUGVPHGGGD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14842937

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

320.35

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

1.572

Distribution Coefficient, logD

1.572

Water Solubility, LogSw

-2.23

Polar Surface Area

56.967

Acid Dissociation Constant (pKa)

12.08

Base Dissociation Constant (pKb)

4.27

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

E146-1163 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • Receptor's ligands
Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Immune system
Targets:
  • Proteases
Agro:
  • Agro

References: we are preparing a list of scientific research reports with E146-1163 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E146-1163?
Check Price and Availability of E146-1163, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E146-1163 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E146-1163
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E146-1163
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E146-1163 available by request