E146-1176 Screening compound: 3,5-dimethyl-1-{1-methyl-1H,4H-chromeno[4,3-c]pyrazole-3-carbonyl}piperidine

E146-1176 Screening compound: 3,5-dimethyl-1-{1-methyl-1H,4H-chromeno[4,3-c]pyrazole-3-carbonyl}piperidine
E146-1176 Screening compound: 3,5-dimethyl-1-{1-methyl-1H,4H-chromeno[4,3-c]pyrazole-3-carbonyl}piperidine alternative view

Chemical Structure Depiction of ChemDiv screening compound E146-1176
3,5-dimethyl-1-{1-methyl-1H,4H-chromeno[4,3-c]pyrazole-3-carbonyl}piperidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E146-1176

Molecular Formula

C19H23N3O2 (C19 H23 N3 O2)

Compound Name

3,5-dimethyl-1-{1-methyl-1H,4H-chromeno[4,3-c]pyrazole-3-carbonyl}piperidine

IUPAC name

35-dimethyl-1-{1-methyl-1H4H-chromeno[43-c]pyrazole-3-carbonyl}piperidine

SMILES

CC(CC(C)C1)CN1C(c1nn(C)c-2c1COc1c2cccc1)=O

InChI

InChI=1S/C19H23N3O2/c1-12-8-13(2)10-22(9-12)19(23)17-15-11-24-16-7-5-4-6-14(16)18(15)21(3)20-17/h4-7,12-13H,8-11H2,1-3H3

InChI Key

YHDWOPHWJHTATN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14842949

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

325.41

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.923

Distribution Coefficient, logD

2.923

Water Solubility, LogSw

-3.54

Polar Surface Area

39.526

Acid Dissociation Constant (pKa)

19.18

Base Dissociation Constant (pKb)

-1.52

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

47.40

E146-1176 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • Receptor's ligands
  • Epigenetic
Therapeutical areas:
  • Immune system
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic

References: we are preparing a list of scientific research reports with E146-1176 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E146-1176?
Check Price and Availability of E146-1176, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E146-1176 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E146-1176
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E146-1176
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E146-1176 available by request