E146-1480 Screening compound: ethyl 4-{1-methyl-1H,4H-thiochromeno[4,3-c]pyrazole-3-carbonyl}piperazine-1-carboxylate

E146-1480 Screening compound: ethyl 4-{1-methyl-1H,4H-thiochromeno[4,3-c]pyrazole-3-carbonyl}piperazine-1-carboxylate
E146-1480 Screening compound: ethyl 4-{1-methyl-1H,4H-thiochromeno[4,3-c]pyrazole-3-carbonyl}piperazine-1-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound E146-1480
ethyl 4-{1-methyl-1H,4H-thiochromeno[4,3-c]pyrazole-3-carbonyl}piperazine-1-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E146-1480

Molecular Formula

C19H22N4O3S (C19 H22 N4 O3 S)

Compound Name

ethyl 4-{1-methyl-1H,4H-thiochromeno[4,3-c]pyrazole-3-carbonyl}piperazine-1-carboxylate

IUPAC name

ethyl 4-{1-methyl-1H4H-thiochromeno[43-c]pyrazole-3-carbonyl}piperazine-1-carboxylate

SMILES

CCOC(N(CC1)CCN1C(c1nn(C)c-2c1CSc1c2cccc1)=O)=O

InChI

InChI=1S/C19H22N4O3S/c1-3-26-19(25)23-10-8-22(9-11-23)18(24)16-14-12-27-15-7-5-4-6-13(15)17(14)21(2)20-16/h4-7H,3,8-12H2,1-2H3

InChI Key

LXYBKRIBBLDWMR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14843188

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

386.47

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.058

Distribution Coefficient, logD

2.058

Water Solubility, LogSw

-2.61

Polar Surface Area

53.990

Acid Dissociation Constant (pKa)

19.18

Base Dissociation Constant (pKb)

-1.52

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

42.10

E146-1480 in Drug Discovery

Included in Screening Libraries

Antiviral Annotated Library (21441 compounds)

Dark Chemical Matter Library (18430 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Structure:
  • Pool

References: we are preparing a list of scientific research reports with E146-1480 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E146-1480?
Check Price and Availability of E146-1480, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E146-1480 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E146-1480
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E146-1480
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E146-1480 available by request