E151-0127 Screening compound: 2,4-dimethyl-N-({8-methylimidazo[1,2-a]pyridin-2-yl}methyl)benzene-1-sulfonamide

E151-0127 Screening compound: 2,4-dimethyl-N-({8-methylimidazo[1,2-a]pyridin-2-yl}methyl)benzene-1-sulfonamide
E151-0127 Screening compound: 2,4-dimethyl-N-({8-methylimidazo[1,2-a]pyridin-2-yl}methyl)benzene-1-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E151-0127
2,4-dimethyl-N-({8-methylimidazo[1,2-a]pyridin-2-yl}methyl)benzene-1-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E151-0127

Molecular Formula

C17H19N3O2S (C17 H19 N3 O2 S)

Compound Name

2,4-dimethyl-N-({8-methylimidazo[1,2-a]pyridin-2-yl}methyl)benzene-1-sulfonamide

IUPAC name

24-dimethyl-N-({8-methylimidazo[12-a]pyridin-2-yl}methyl)benzene-1-sulfonamide

SMILES

Cc(cc1)cc(C)c1S(NCc1cn(cccc2C)c2n1)(=O)=O

InChI

InChI=1S/C17H19N3O2S/c1-12-6-7-16(14(3)9-12)23(21,22)18-10-15-11-20-8-4-5-13(2)17(20)19-15/h4-9,11,18H,10H2,1-3H3

InChI Key

KJDDBRSKEJMKDU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD05720037

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

329.42

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.656

Distribution Coefficient, logD

3.194

Water Solubility, LogSw

-3.55

Polar Surface Area

52.705

Acid Dissociation Constant (pKa)

9.08

Base Dissociation Constant (pKb)

7.68

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.50

E151-0127 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Indoleamine 2,3-dioxygenase 1 Focused Library (5816 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Immune system
Targets:
  • Others

References: we are preparing a list of scientific research reports with E151-0127 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E151-0127?
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What is the minimum amount of E151-0127 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E151-0127
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E151-0127
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E151-0127 available by request