E153-0115 Screening compound: 2,2,2-trifluoro-N-(3-{[1,3]thiazolo[5,4-b]pyridin-2-yl}phenyl)acetamide

E153-0115 Screening compound: 2,2,2-trifluoro-N-(3-{[1,3]thiazolo[5,4-b]pyridin-2-yl}phenyl)acetamide
E153-0115 Screening compound: 2,2,2-trifluoro-N-(3-{[1,3]thiazolo[5,4-b]pyridin-2-yl}phenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E153-0115
2,2,2-trifluoro-N-(3-{[1,3]thiazolo[5,4-b]pyridin-2-yl}phenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E153-0115

Molecular Formula

C14H8F3N3OS (C14 H8 F3 N3 OS)

Compound Name

2,2,2-trifluoro-N-(3-{[1,3]thiazolo[5,4-b]pyridin-2-yl}phenyl)acetamide

IUPAC name

222-trifluoro-N-(3-{[13]thiazolo[54-b]pyridin-2-yl}phenyl)acetamide

SMILES

O=C(C(F)(F)F)Nc1cccc(-c2nc3cccnc3s2)c1

InChI

InChI=1S/C14H8F3N3OS/c15-14(16,17)13(21)19-9-4-1-3-8(7-9)11-20-10-5-2-6-18-12(10)22-11/h1-7H,(H,19,21)

InChI Key

MTYQHCUQBYIICX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD05894395

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

323.3

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

3.733

Distribution Coefficient, logD

3.727

Water Solubility, LogSw

-4.20

Polar Surface Area

42.456

Acid Dissociation Constant (pKa)

9.25

Base Dissociation Constant (pKb)

2.55

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

7.10

E153-0115 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Agro:
  • Agro

References: we are preparing a list of scientific research reports with E153-0115 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E153-0115?
Check Price and Availability of E153-0115, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E153-0115 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E153-0115
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E153-0115
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E153-0115 available by request