E153-0411 Screening compound: N-(2-methyl-3-{[1,3]thiazolo[5,4-b]pyridin-2-yl}phenyl)-9H-xanthene-9-carboxamide

E153-0411 Screening compound: N-(2-methyl-3-{[1,3]thiazolo[5,4-b]pyridin-2-yl}phenyl)-9H-xanthene-9-carboxamide
E153-0411 Screening compound: N-(2-methyl-3-{[1,3]thiazolo[5,4-b]pyridin-2-yl}phenyl)-9H-xanthene-9-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E153-0411
N-(2-methyl-3-{[1,3]thiazolo[5,4-b]pyridin-2-yl}phenyl)-9H-xanthene-9-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E153-0411

Molecular Formula

C27H19N3O2S (C27 H19 N3 O2 S)

Compound Name

N-(2-methyl-3-{[1,3]thiazolo[5,4-b]pyridin-2-yl}phenyl)-9H-xanthene-9-carboxamide

IUPAC name

N-(2-methyl-3-{[13]thiazolo[54-b]pyridin-2-yl}phenyl)-9H-xanthene-9-carboxamide

SMILES

Cc(c(NC(C1c(cccc2)c2Oc2c1cccc2)=O)ccc1)c1-c1nc2cccnc2s1

InChI

InChI=1S/C27H19N3O2S/c1-16-17(26-30-21-12-7-15-28-27(21)33-26)10-6-11-20(16)29-25(31)24-18-8-2-4-13-22(18)32-23-14-5-3-9-19(23)24/h2-15,24H,1H3,(H,29,31)

InChI Key

GIEVSVKDHNJGIO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD05909709

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

449.53

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.716

Distribution Coefficient, logD

-1.584

Water Solubility, LogSw

-5.50

Polar Surface Area

48.300

Acid Dissociation Constant (pKa)

-3.68

Base Dissociation Constant (pKb)

3.30

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

7.40

E153-0411 in Drug Discovery

Included in Screening Libraries

Protein-Protein Interaction Library (218420 compounds)

Chemokine Receptor-Targeted Library (18382 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • Receptor's ligands
Therapeutical areas:
  • Immune system

References: we are preparing a list of scientific research reports with E153-0411 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E153-0411?
Check Price and Availability of E153-0411, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E153-0411 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E153-0411
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E153-0411
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E153-0411 available by request