E153-0424 Screening compound: N-(2-methyl-3-{[1,3]thiazolo[5,4-b]pyridin-2-yl}phenyl)-2H-1,3-benzodioxole-5-carboxamide

E153-0424 Screening compound: N-(2-methyl-3-{[1,3]thiazolo[5,4-b]pyridin-2-yl}phenyl)-2H-1,3-benzodioxole-5-carboxamide
E153-0424 Screening compound: N-(2-methyl-3-{[1,3]thiazolo[5,4-b]pyridin-2-yl}phenyl)-2H-1,3-benzodioxole-5-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E153-0424
N-(2-methyl-3-{[1,3]thiazolo[5,4-b]pyridin-2-yl}phenyl)-2H-1,3-benzodioxole-5-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E153-0424

Molecular Formula

C21H15N3O3S (C21 H15 N3 O3 S)

Compound Name

N-(2-methyl-3-{[1,3]thiazolo[5,4-b]pyridin-2-yl}phenyl)-2H-1,3-benzodioxole-5-carboxamide

IUPAC name

N-(2-methyl-3-{[13]thiazolo[54-b]pyridin-2-yl}phenyl)-2H-13-benzodioxole-5-carboxamide

SMILES

Cc(c(NC(c(cc1)cc2c1OCO2)=O)ccc1)c1-c1nc2cccnc2s1

InChI

InChI=1S/C21H15N3O3S/c1-12-14(20-24-16-6-3-9-22-21(16)28-20)4-2-5-15(12)23-19(25)13-7-8-17-18(10-13)27-11-26-17/h2-10H,11H2,1H3,(H,23,25)

InChI Key

VPXANLRJEVUZTD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD05894479

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

389.43

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.425

Distribution Coefficient, logD

4.425

Water Solubility, LogSw

-4.30

Polar Surface Area

58.602

Acid Dissociation Constant (pKa)

12.38

Base Dissociation Constant (pKb)

3.30

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.50

E153-0424 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with E153-0424 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E153-0424?
Check Price and Availability of E153-0424, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E153-0424 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E153-0424
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E153-0424
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E153-0424 available by request