E153-0429 Screening compound: 2-(4-chlorophenyl)-N-(2-methyl-3-{[1,3]thiazolo[5,4-b]pyridin-2-yl}phenyl)acetamide

E153-0429 Screening compound: 2-(4-chlorophenyl)-N-(2-methyl-3-{[1,3]thiazolo[5,4-b]pyridin-2-yl}phenyl)acetamide
E153-0429 Screening compound: 2-(4-chlorophenyl)-N-(2-methyl-3-{[1,3]thiazolo[5,4-b]pyridin-2-yl}phenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E153-0429
2-(4-chlorophenyl)-N-(2-methyl-3-{[1,3]thiazolo[5,4-b]pyridin-2-yl}phenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E153-0429

Molecular Formula

C21H16ClN3OS (C21 H16 ClN3 OS)

Compound Name

2-(4-chlorophenyl)-N-(2-methyl-3-{[1,3]thiazolo[5,4-b]pyridin-2-yl}phenyl)acetamide

IUPAC name

2-(4-chlorophenyl)-N-(2-methyl-3-{[13]thiazolo[54-b]pyridin-2-yl}phenyl)acetamide

SMILES

Cc(c(-c1nc(cccn2)c2s1)ccc1)c1NC(Cc(cc1)ccc1Cl)=O

InChI

InChI=1S/C21H16ClN3OS/c1-13-16(20-25-18-6-3-11-23-21(18)27-20)4-2-5-17(13)24-19(26)12-14-7-9-15(22)10-8-14/h2-11H,12H2,1H3,(H,24,26)

InChI Key

RJBZPICECMNGPZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD05894483

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

393.9

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

4.788

Distribution Coefficient, logD

4.788

Water Solubility, LogSw

-4.91

Polar Surface Area

41.273

Acid Dissociation Constant (pKa)

12.36

Base Dissociation Constant (pKb)

3.30

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.50

E153-0429 in Drug Discovery

Included in Screening Libraries

Selective Target Activity Profiling Library (14702 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with E153-0429 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E153-0429?
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What is the minimum amount of E153-0429 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E153-0429
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E153-0429
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E153-0429 available by request