E157-2648 Screening compound: 2-(4-chlorophenoxy)-N-[5-(2,3-dihydro-1H-indole-1-sulfonyl)-1,3,4-thiadiazol-2-yl]acetamide

E157-2648 Screening compound: 2-(4-chlorophenoxy)-N-[5-(2,3-dihydro-1H-indole-1-sulfonyl)-1,3,4-thiadiazol-2-yl]acetamide
E157-2648 Screening compound: 2-(4-chlorophenoxy)-N-[5-(2,3-dihydro-1H-indole-1-sulfonyl)-1,3,4-thiadiazol-2-yl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E157-2648
2-(4-chlorophenoxy)-N-[5-(2,3-dihydro-1H-indole-1-sulfonyl)-1,3,4-thiadiazol-2-yl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E157-2648

Molecular Formula

C18H15ClN4O4S2 (C18 H15 ClN4 O4 S2)

Compound Name

2-(4-chlorophenoxy)-N-[5-(2,3-dihydro-1H-indole-1-sulfonyl)-1,3,4-thiadiazol-2-yl]acetamide

IUPAC name

2-(4-chlorophenoxy)-N-[5-(23-dihydro-1H-indole-1-sulfonyl)-134-thiadiazol-2-yl]acetamide

SMILES

O=C(COc(cc1)ccc1Cl)Nc(s1)nnc1S(N(CC1)c2c1cccc2)(=O)=O

InChI

InChI=1S/C18H15ClN4O4S2/c19-13-5-7-14(8-6-13)27-11-16(24)20-17-21-22-18(28-17)29(25,26)23-10-9-12-3-1-2-4-15(12)23/h1-8H,9-11H2,(H,20,21,24)

InChI Key

FCRLFVIYOBCLEE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14843630

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

450.93

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.939

Distribution Coefficient, logD

3.681

Water Solubility, LogSw

-4.50

Polar Surface Area

85.453

Acid Dissociation Constant (pKa)

7.49

Base Dissociation Constant (pKb)

-6.31

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

E157-2648 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Antiviral Annotated Library (21441 compounds)

Human Receptors Annotated Library (5376 compounds)

Human Transcription Factors Annotated Library (5098 compounds)

Selective Target Activity Profiling Library (14702 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin

References: we are preparing a list of scientific research reports with E157-2648 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E157-2648?
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What is the minimum amount of E157-2648 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E157-2648
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E157-2648
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E157-2648 available by request