E157-2741 Screening compound: N-{5-[(2-methyl-2,3-dihydro-1H-indol-1-yl)sulfonyl]-1,3,4-thiadiazol-2-yl}-3-nitrobenzamide

E157-2741 Screening compound: N-{5-[(2-methyl-2,3-dihydro-1H-indol-1-yl)sulfonyl]-1,3,4-thiadiazol-2-yl}-3-nitrobenzamide
E157-2741 Screening compound: N-{5-[(2-methyl-2,3-dihydro-1H-indol-1-yl)sulfonyl]-1,3,4-thiadiazol-2-yl}-3-nitrobenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E157-2741
N-{5-[(2-methyl-2,3-dihydro-1H-indol-1-yl)sulfonyl]-1,3,4-thiadiazol-2-yl}-3-nitrobenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E157-2741

Molecular Formula

C18H15N5O5S2 (C18 H15 N5 O5 S2)

Compound Name

N-{5-[(2-methyl-2,3-dihydro-1H-indol-1-yl)sulfonyl]-1,3,4-thiadiazol-2-yl}-3-nitrobenzamide

IUPAC name

N-{5-[(2-methyl-23-dihydro-1H-indol-1-yl)sulfonyl]-134-thiadiazol-2-yl}-3-nitrobenzamide

SMILES

CC(Cc1c2cccc1)N2S(c1nnc(NC(c2cc([N+]([O-])=O)ccc2)=O)s1)(=O)=O

InChI

InChI=1S/C18H15N5O5S2/c1-11-9-12-5-2-3-8-15(12)22(11)30(27,28)18-21-20-17(29-18)19-16(24)13-6-4-7-14(10-13)23(25)26/h2-8,10-11H,9H2,1H3,(H,19,20,24)/t11-/m0/s1

InChI Key

ACNMDXXBEJJSEJ-NSHDSACASA-N

MDL Number (MFCD)

MFCD14843657

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

445.48

Hydrogen Bond Acceptors Count

12.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

3.969

Distribution Coefficient, logD

1.465

Water Solubility, LogSw

-4.16

Polar Surface Area

111.265

Acid Dissociation Constant (pKa)

4.90

Base Dissociation Constant (pKb)

-8.74

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

16.70

E157-2741 in Drug Discovery

Included in Screening Libraries

Antiparasite Library (23996 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
Agro:
  • Agro

References: we are preparing a list of scientific research reports with E157-2741 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E157-2741?
Check Price and Availability of E157-2741, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E157-2741 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E157-2741
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E157-2741
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E157-2741 available by request