E157-3565 Screening compound: 2-methoxy-N-[3-(3-methoxyphenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl]benzamide

E157-3565 Screening compound: 2-methoxy-N-[3-(3-methoxyphenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl]benzamide
E157-3565 Screening compound: 2-methoxy-N-[3-(3-methoxyphenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E157-3565
2-methoxy-N-[3-(3-methoxyphenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E157-3565

Molecular Formula

C18H15N5O3S (C18 H15 N5 O3 S)

Compound Name

2-methoxy-N-[3-(3-methoxyphenyl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl]benzamide

IUPAC name

2-methoxy-N-[3-(3-methoxyphenyl)-[124]triazolo[34-b][134]thiadiazol-6-yl]benzamide

SMILES

COc1cccc(-c2nnc3sc(NC(c(cccc4)c4OC)=O)nn23)c1

InChI

InChI=1S/C18H15N5O3S/c1-25-12-7-5-6-11(10-12)15-20-21-18-23(15)22-17(27-18)19-16(24)13-8-3-4-9-14(13)26-2/h3-10H,1-2H3,(H,19,22,24)

InChI Key

DRPSJKBONFEGHS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14843833

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

381.42

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.188

Distribution Coefficient, logD

2.832

Water Solubility, LogSw

-3.83

Polar Surface Area

72.299

Acid Dissociation Constant (pKa)

7.30

Base Dissociation Constant (pKb)

2.26

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.10

E157-3565 in Drug Discovery

Included in Screening Libraries

Proline Kinase Library (2105 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Nervous system
  • Male
  • Female
  • Endocrine
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with E157-3565 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E157-3565?
Check Price and Availability of E157-3565, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E157-3565 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E157-3565
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E157-3565
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E157-3565 available by request