E157-3599 Screening compound: N-[3-(furan-2-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl]-3-methoxybenzamide

E157-3599 Screening compound: N-[3-(furan-2-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl]-3-methoxybenzamide
E157-3599 Screening compound: N-[3-(furan-2-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl]-3-methoxybenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E157-3599
N-[3-(furan-2-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl]-3-methoxybenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E157-3599

Molecular Formula

C15H11N5O3S (C15 H11 N5 O3 S)

Compound Name

N-[3-(furan-2-yl)-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazol-6-yl]-3-methoxybenzamide

IUPAC name

N-[3-(furan-2-yl)-[124]triazolo[34-b][134]thiadiazol-6-yl]-3-methoxybenzamide

SMILES

COc1cccc(C(Nc(s2)nn3c2nnc3-c2ccco2)=O)c1

InChI

InChI=1S/C15H11N5O3S/c1-22-10-5-2-4-9(8-10)13(21)16-14-19-20-12(11-6-3-7-23-11)17-18-15(20)24-14/h2-8H,1H3,(H,16,19,21)

InChI Key

JBBSFJXAWSOCCU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14843846

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

341.35

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.314

Distribution Coefficient, logD

2.304

Water Solubility, LogSw

-3.06

Polar Surface Area

73.247

Acid Dissociation Constant (pKa)

9.01

Base Dissociation Constant (pKb)

-1.13

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

6.70

E157-3599 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

C-Met Library (15277 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
Mechanism of action:
  • Epigenetic
  • Receptor's ligands
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with E157-3599 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E157-3599?
Check Price and Availability of E157-3599, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E157-3599 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E157-3599
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E157-3599
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E157-3599 available by request