E157-6090 Screening compound: 3,4,5-trimethoxy-N-{5-[methyl(3-methylphenyl)sulfamoyl]-1,3,4-thiadiazol-2-yl}benzamide

E157-6090 Screening compound: 3,4,5-trimethoxy-N-{5-[methyl(3-methylphenyl)sulfamoyl]-1,3,4-thiadiazol-2-yl}benzamide
E157-6090 Screening compound: 3,4,5-trimethoxy-N-{5-[methyl(3-methylphenyl)sulfamoyl]-1,3,4-thiadiazol-2-yl}benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E157-6090
3,4,5-trimethoxy-N-{5-[methyl(3-methylphenyl)sulfamoyl]-1,3,4-thiadiazol-2-yl}benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E157-6090

Molecular Formula

C20H22N4O6S2 (C20 H22 N4 O6 S2)

Compound Name

3,4,5-trimethoxy-N-{5-[methyl(3-methylphenyl)sulfamoyl]-1,3,4-thiadiazol-2-yl}benzamide

IUPAC name

345-trimethoxy-N-{5-[methyl(3-methylphenyl)sulfamoyl]-134-thiadiazol-2-yl}benzamide

SMILES

Cc1cccc(N(C)S(c2nnc(NC(c(cc3OC)cc(OC)c3OC)=O)s2)(=O)=O)c1

InChI

InChI=1S/C20H22N4O6S2/c1-12-7-6-8-14(9-12)24(2)32(26,27)20-23-22-19(31-20)21-18(25)13-10-15(28-3)17(30-5)16(11-13)29-4/h6-11H,1-5H3,(H,21,22,25)

InChI Key

KUZURRAIDMMTEK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14844205

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

478.55

Hydrogen Bond Acceptors Count

11.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

3.814

Distribution Coefficient, logD

3.584

Water Solubility, LogSw

-3.99

Polar Surface Area

102.448

Acid Dissociation Constant (pKa)

7.56

Base Dissociation Constant (pKb)

-8.49

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.00

E157-6090 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin

References: we are preparing a list of scientific research reports with E157-6090 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E157-6090?
Check Price and Availability of E157-6090, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E157-6090 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E157-6090
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E157-6090
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E157-6090 available by request