E157-6656 Screening compound: 2-(4-chlorophenoxy)-N-{5-[ethyl(4-methoxyphenyl)sulfamoyl]-1,3,4-thiadiazol-2-yl}acetamide

E157-6656 Screening compound: 2-(4-chlorophenoxy)-N-{5-[ethyl(4-methoxyphenyl)sulfamoyl]-1,3,4-thiadiazol-2-yl}acetamide
E157-6656 Screening compound: 2-(4-chlorophenoxy)-N-{5-[ethyl(4-methoxyphenyl)sulfamoyl]-1,3,4-thiadiazol-2-yl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E157-6656
2-(4-chlorophenoxy)-N-{5-[ethyl(4-methoxyphenyl)sulfamoyl]-1,3,4-thiadiazol-2-yl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E157-6656

Molecular Formula

C19H19ClN4O5S2 (C19 H19 ClN4 O5 S2)

Compound Name

2-(4-chlorophenoxy)-N-{5-[ethyl(4-methoxyphenyl)sulfamoyl]-1,3,4-thiadiazol-2-yl}acetamide

IUPAC name

2-(4-chlorophenoxy)-N-{5-[ethyl(4-methoxyphenyl)sulfamoyl]-134-thiadiazol-2-yl}acetamide

SMILES

CCN(c(cc1)ccc1OC)S(c1nnc(NC(COc(cc2)ccc2Cl)=O)s1)(=O)=O

InChI

InChI=1S/C19H19ClN4O5S2/c1-3-24(14-6-10-15(28-2)11-7-14)31(26,27)19-23-22-18(30-19)21-17(25)12-29-16-8-4-13(20)5-9-16/h4-11H,3,12H2,1-2H3,(H,21,22,25)

InChI Key

JJZPJDYGUKEILX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14844309

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

482.97

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

4.229

Distribution Coefficient, logD

3.972

Water Solubility, LogSw

-4.47

Polar Surface Area

93.029

Acid Dissociation Constant (pKa)

7.49

Base Dissociation Constant (pKb)

-6.31

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.10

E157-6656 in Drug Discovery

Included in Screening Libraries

Human GPCR Annotated Library (5539 compounds)

Human Proteases Annotated Library (2868 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with E157-6656 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E157-6656?
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What is the minimum amount of E157-6656 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E157-6656
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E157-6656
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E157-6656 available by request