E157-8163 Screening compound: 3-chloro-N-(5-{[(furan-2-yl)methyl](methyl)sulfamoyl}-1,3,4-thiadiazol-2-yl)benzamide

E157-8163 Screening compound: 3-chloro-N-(5-{[(furan-2-yl)methyl](methyl)sulfamoyl}-1,3,4-thiadiazol-2-yl)benzamide
E157-8163 Screening compound: 3-chloro-N-(5-{[(furan-2-yl)methyl](methyl)sulfamoyl}-1,3,4-thiadiazol-2-yl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E157-8163
3-chloro-N-(5-{[(furan-2-yl)methyl](methyl)sulfamoyl}-1,3,4-thiadiazol-2-yl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E157-8163

Molecular Formula

C15H13ClN4O4S2 (C15 H13 ClN4 O4 S2)

Compound Name

3-chloro-N-(5-{[(furan-2-yl)methyl](methyl)sulfamoyl}-1,3,4-thiadiazol-2-yl)benzamide

IUPAC name

3-chloro-N-(5-{[(furan-2-yl)methyl](methyl)sulfamoyl}-134-thiadiazol-2-yl)benzamide

SMILES

CN(Cc1ccco1)S(c1nnc(NC(c2cccc(Cl)c2)=O)s1)(=O)=O

InChI

InChI=1S/C15H13ClN4O4S2/c1-20(9-12-6-3-7-24-12)26(22,23)15-19-18-14(25-15)17-13(21)10-4-2-5-11(16)8-10/h2-8H,9H2,1H3,(H,17,18,21)

InChI Key

NGZVAMVDWKERAG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14844395

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

412.88

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.502

Distribution Coefficient, logD

1.000

Water Solubility, LogSw

-3.98

Polar Surface Area

86.962

Acid Dissociation Constant (pKa)

4.90

Base Dissociation Constant (pKb)

-7.11

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

13.30

E157-8163 in Drug Discovery

Included in Screening Libraries

Selective Target Activity Profiling Library (14702 compounds)

Therapeutical Diversity Annotated Library (7563 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with E157-8163 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E157-8163?
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What is the minimum amount of E157-8163 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E157-8163
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E157-8163
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E157-8163 available by request