E157-8175 Screening compound: N-(5-{[(furan-2-yl)methyl](methyl)sulfamoyl}-1,3,4-thiadiazol-2-yl)butanamide

E157-8175 Screening compound: N-(5-{[(furan-2-yl)methyl](methyl)sulfamoyl}-1,3,4-thiadiazol-2-yl)butanamide
E157-8175 Screening compound: N-(5-{[(furan-2-yl)methyl](methyl)sulfamoyl}-1,3,4-thiadiazol-2-yl)butanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E157-8175
N-(5-{[(furan-2-yl)methyl](methyl)sulfamoyl}-1,3,4-thiadiazol-2-yl)butanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E157-8175

Molecular Formula

C12H16N4O4S2 (C12 H16 N4 O4 S2)

Compound Name

N-(5-{[(furan-2-yl)methyl](methyl)sulfamoyl}-1,3,4-thiadiazol-2-yl)butanamide

IUPAC name

N-(5-{[(furan-2-yl)methyl](methyl)sulfamoyl}-134-thiadiazol-2-yl)butanamide

SMILES

CCCC(Nc(s1)nnc1S(N(C)Cc1ccco1)(=O)=O)=O

InChI

InChI=1S/C12H16N4O4S2/c1-3-5-10(17)13-11-14-15-12(21-11)22(18,19)16(2)8-9-6-4-7-20-9/h4,6-7H,3,5,8H2,1-2H3,(H,13,14,17)

InChI Key

RJVYGHHUJJGLNN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14844400

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

344.42

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.095

Distribution Coefficient, logD

1.625

Water Solubility, LogSw

-2.84

Polar Surface Area

87.021

Acid Dissociation Constant (pKa)

7.11

Base Dissociation Constant (pKb)

-6.29

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

41.70

E157-8175 in Drug Discovery

Included in Screening Libraries

CNS MPO Library (28609 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with E157-8175 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E157-8175?
Check Price and Availability of E157-8175, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E157-8175 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E157-8175
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E157-8175
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E157-8175 available by request