E197-0329 Screening compound: N-(4-chloro-2-fluorophenyl)-2-(N-methyl1,3,3-trimethyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamido)acetamide

E197-0329 Screening compound: N-(4-chloro-2-fluorophenyl)-2-(N-methyl1,3,3-trimethyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamido)acetamide
E197-0329 Screening compound: N-(4-chloro-2-fluorophenyl)-2-(N-methyl1,3,3-trimethyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamido)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E197-0329
N-(4-chloro-2-fluorophenyl)-2-(N-methyl1,3,3-trimethyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamido)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E197-0329

Molecular Formula

C20H21ClFN3O4S (C20 H21 ClFN3 O4 S)

Compound Name

N-(4-chloro-2-fluorophenyl)-2-(N-methyl1,3,3-trimethyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamido)acetamide

IUPAC name

N-(4-chloro-2-fluorophenyl)-2-(N-methyl133-trimethyl-2-oxo-23-dihydro-1H-indole-5-sulfonamido)acetamide

SMILES

CC(C)(c(cc(cc1)S(N(C)CC(Nc(ccc(Cl)c2)c2F)=O)(=O)=O)c1N1C)C1=O

InChI

InChI=1S/C20H21ClFN3O4S/c1-20(2)14-10-13(6-8-17(14)25(4)19(20)27)30(28,29)24(3)11-18(26)23-16-7-5-12(21)9-15(16)22/h5-10H,11H2,1-4H3,(H,23,26)

InChI Key

IOJQYJAWRPNCBW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14844972

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

453.92

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.283

Distribution Coefficient, logD

3.211

Water Solubility, LogSw

-3.83

Polar Surface Area

70.760

Acid Dissociation Constant (pKa)

8.14

Base Dissociation Constant (pKb)

-2.56

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.00

E197-0329 in Drug Discovery

Included in Screening Libraries

SH2 Library (10483 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Endocrine
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with E197-0329 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E197-0329?
Check Price and Availability of E197-0329, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E197-0329 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E197-0329
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E197-0329
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E197-0329 available by request