E201-0177 Screening compound: ethyl 2-(2-{[(1-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidin-2-yl)carbonyl]amino}-1,3-thiazol-4-yl)acetate

E201-0177 Screening compound: ethyl 2-(2-{[(1-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidin-2-yl)carbonyl]amino}-1,3-thiazol-4-yl)acetate
E201-0177 Screening compound: ethyl 2-(2-{[(1-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidin-2-yl)carbonyl]amino}-1,3-thiazol-4-yl)acetate alternative view

Chemical Structure Depiction of ChemDiv screening compound E201-0177
ethyl 2-(2-{[(1-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidin-2-yl)carbonyl]amino}-1,3-thiazol-4-yl)acetate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E201-0177

Molecular Formula

C19H17N5O4S (C19 H17 N5 O4 S)

Compound Name

ethyl 2-(2-{[(1-methyl-4-oxo-1,4-dihydropyrido[1,2-a]pyrrolo[2,3-d]pyrimidin-2-yl)carbonyl]amino}-1,3-thiazol-4-yl)acetate

IUPAC name

ethyl 2-(2-{6-methyl-2-oxo-168-triazatricyclo[7.4.0.0^{37}]trideca-3(7)481012-pentaene-5-amido}-13-thiazol-4-yl)acetate

SMILES

CCOC(Cc1csc(NC(c(n2C)cc3c2N=C(C=CC=C2)N2C3=O)=O)n1)=O

InChI

InChI=1S/C19H17N5O4S/c1-3-28-15(25)8-11-10-29-19(20-11)22-17(26)13-9-12-16(23(13)2)21-14-6-4-5-7-24(14)18(12)27/h4-7,9-10H,3,8H2,1-2H3,(H,20,22,26)

InChI Key

OLIZFGAJEHCLNY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD05894977

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

411.44

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.366

Distribution Coefficient, logD

2.014

Water Solubility, LogSw

-2.97

Polar Surface Area

81.194

Acid Dissociation Constant (pKa)

7.30

Base Dissociation Constant (pKb)

0.08

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.10

E201-0177 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Nucleoside Mimetics Library (2197 compounds)

Purine Based Nucleoside Mimetics Library (1131 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Antiviral
  • Infections
  • Cancer
  • Immune system
Targets:
  • Kinases
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with E201-0177 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E201-0177?
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What is the minimum amount of E201-0177 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E201-0177
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E201-0177
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E201-0177 available by request