E201-0231 Screening compound: 2-{[4-(2-fluorophenyl)piperazino]carbonyl}-1,9-dimethylpyrido[1,2-a]pyrrolo[2,3-d]pyrimidin-4(1H)-one

E201-0231 Screening compound: 2-{[4-(2-fluorophenyl)piperazino]carbonyl}-1,9-dimethylpyrido[1,2-a]pyrrolo[2,3-d]pyrimidin-4(1H)-one
E201-0231 Screening compound: 2-{[4-(2-fluorophenyl)piperazino]carbonyl}-1,9-dimethylpyrido[1,2-a]pyrrolo[2,3-d]pyrimidin-4(1H)-one alternative view

Chemical Structure Depiction of ChemDiv screening compound E201-0231
2-{[4-(2-fluorophenyl)piperazino]carbonyl}-1,9-dimethylpyrido[1,2-a]pyrrolo[2,3-d]pyrimidin-4(1H)-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E201-0231

Molecular Formula

C23H22FN5O2 (C23 H22 FN5 O2)

Compound Name

2-{[4-(2-fluorophenyl)piperazino]carbonyl}-1,9-dimethylpyrido[1,2-a]pyrrolo[2,3-d]pyrimidin-4(1H)-one

IUPAC name

5-[4-(2-fluorophenyl)piperazine-1-carbonyl]-610-dimethyl-168-triazatricyclo[7.4.0.0^{37}]trideca-3(7)481012-pentaen-2-one

SMILES

CC1=CC=CN2C1=Nc(n(C)c(C(N(CC1)CCN1c(cccc1)c1F)=O)c1)c1C2=O

InChI

InChI=1S/C23H22FN5O2/c1-15-6-5-9-29-20(15)25-21-16(22(29)30)14-19(26(21)2)23(31)28-12-10-27(11-13-28)18-8-4-3-7-17(18)24/h3-9,14H,10-13H2,1-2H3

InChI Key

XHNTZOQWCPQWFC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD05895017

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

419.46

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.805

Distribution Coefficient, logD

2.805

Water Solubility, LogSw

-3.37

Polar Surface Area

46.031

Acid Dissociation Constant (pKa)

28.47

Base Dissociation Constant (pKb)

2.12

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.10

E201-0231 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with E201-0231 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E201-0231?
Check Price and Availability of E201-0231, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E201-0231 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E201-0231
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E201-0231
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E201-0231 available by request