E203-1113 Screening compound: 4-(2,3-dihydro-1H-indole-1-sulfonyl)-1-methyl-N-[2-methyl-6-(propan-2-yl)phenyl]-1H-pyrrole-2-carboxamide

E203-1113 Screening compound: 4-(2,3-dihydro-1H-indole-1-sulfonyl)-1-methyl-N-[2-methyl-6-(propan-2-yl)phenyl]-1H-pyrrole-2-carboxamide
E203-1113 Screening compound: 4-(2,3-dihydro-1H-indole-1-sulfonyl)-1-methyl-N-[2-methyl-6-(propan-2-yl)phenyl]-1H-pyrrole-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E203-1113
4-(2,3-dihydro-1H-indole-1-sulfonyl)-1-methyl-N-[2-methyl-6-(propan-2-yl)phenyl]-1H-pyrrole-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E203-1113

Molecular Formula

C24H27N3O3S (C24 H27 N3 O3 S)

Compound Name

4-(2,3-dihydro-1H-indole-1-sulfonyl)-1-methyl-N-[2-methyl-6-(propan-2-yl)phenyl]-1H-pyrrole-2-carboxamide

IUPAC name

4-(23-dihydro-1H-indole-1-sulfonyl)-1-methyl-N-[2-methyl-6-(propan-2-yl)phenyl]-1H-pyrrole-2-carboxamide

SMILES

CC(C)c(cccc1C)c1NC(c1cc(S(N(CC2)c3c2cccc3)(=O)=O)cn1C)=O

InChI

InChI=1S/C24H27N3O3S/c1-16(2)20-10-7-8-17(3)23(20)25-24(28)22-14-19(15-26(22)4)31(29,30)27-13-12-18-9-5-6-11-21(18)27/h5-11,14-16H,12-13H2,1-4H3,(H,25,28)

InChI Key

ZKQBZLWOJGITSF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27597738

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

437.56

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.461

Distribution Coefficient, logD

3.461

Water Solubility, LogSw

-3.80

Polar Surface Area

55.762

Acid Dissociation Constant (pKa)

11.21

Base Dissociation Constant (pKb)

-3.06

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.20

E203-1113 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with E203-1113 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E203-1113?
Check Price and Availability of E203-1113, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E203-1113 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E203-1113
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E203-1113
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E203-1113 available by request