E203-1250 Screening compound: 4-(2,3-dihydro-1H-indole-1-sulfonyl)-N-(4-ethoxyphenyl)-1-methyl-N-propyl-1H-pyrrole-2-carboxamide

E203-1250 Screening compound: 4-(2,3-dihydro-1H-indole-1-sulfonyl)-N-(4-ethoxyphenyl)-1-methyl-N-propyl-1H-pyrrole-2-carboxamide
E203-1250 Screening compound: 4-(2,3-dihydro-1H-indole-1-sulfonyl)-N-(4-ethoxyphenyl)-1-methyl-N-propyl-1H-pyrrole-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E203-1250
4-(2,3-dihydro-1H-indole-1-sulfonyl)-N-(4-ethoxyphenyl)-1-methyl-N-propyl-1H-pyrrole-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E203-1250

Molecular Formula

C25H29N3O4S (C25 H29 N3 O4 S)

Compound Name

4-(2,3-dihydro-1H-indole-1-sulfonyl)-N-(4-ethoxyphenyl)-1-methyl-N-propyl-1H-pyrrole-2-carboxamide

IUPAC name

4-(23-dihydro-1H-indole-1-sulfonyl)-N-(4-ethoxyphenyl)-1-methyl-N-propyl-1H-pyrrole-2-carboxamide

SMILES

CCCN(C(c1cc(S(N(CC2)c3c2cccc3)(=O)=O)cn1C)=O)c(cc1)ccc1OCC

InChI

InChI=1S/C25H29N3O4S/c1-4-15-27(20-10-12-21(13-11-20)32-5-2)25(29)24-17-22(18-26(24)3)33(30,31)28-16-14-19-8-6-7-9-23(19)28/h6-13,17-18H,4-5,14-16H2,1-3H3

InChI Key

VQKFRXGJMWPVST-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14845648

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

467.59

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.232

Distribution Coefficient, logD

4.232

Water Solubility, LogSw

-4.01

Polar Surface Area

56.791

Acid Dissociation Constant (pKa)

26.08

Base Dissociation Constant (pKb)

-0.30

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

32.00

E203-1250 in Drug Discovery

Included in Screening Libraries

3D-Biodiversity Library (27607 compounds)

Antimitotic Tubulin Library (17355 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Human Receptors Annotated Library (5376 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Target Identification, Phenotypic Screening library (TIPS) (27612 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with E203-1250 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E203-1250?
Check Price and Availability of E203-1250, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of E203-1250 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E203-1250
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E203-1250
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E203-1250 available by request