E203-1467 Screening compound: N-[(pyridin-3-yl)methyl]-1-[(1,3,3-trimethyl-2-oxo-2,3-dihydro-1H-indol-5-yl)sulfonyl]piperidine-3-carboxamide

E203-1467 Screening compound: N-[(pyridin-3-yl)methyl]-1-[(1,3,3-trimethyl-2-oxo-2,3-dihydro-1H-indol-5-yl)sulfonyl]piperidine-3-carboxamide
E203-1467 Screening compound: N-[(pyridin-3-yl)methyl]-1-[(1,3,3-trimethyl-2-oxo-2,3-dihydro-1H-indol-5-yl)sulfonyl]piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E203-1467
N-[(pyridin-3-yl)methyl]-1-[(1,3,3-trimethyl-2-oxo-2,3-dihydro-1H-indol-5-yl)sulfonyl]piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E203-1467

Molecular Formula

C23H28N4O4S (C23 H28 N4 O4 S)

Compound Name

N-[(pyridin-3-yl)methyl]-1-[(1,3,3-trimethyl-2-oxo-2,3-dihydro-1H-indol-5-yl)sulfonyl]piperidine-3-carboxamide

IUPAC name

N-[(pyridin-3-yl)methyl]-1-[(133-trimethyl-2-oxo-23-dihydro-1H-indol-5-yl)sulfonyl]piperidine-3-carboxamide

SMILES

CC(C)(c(cc(cc1)S(N(CCC2)CC2C(NCc2cnccc2)=O)(=O)=O)c1N1C)C1=O

InChI

InChI=1S/C23H28N4O4S/c1-23(2)19-12-18(8-9-20(19)26(3)22(23)29)32(30,31)27-11-5-7-17(15-27)21(28)25-14-16-6-4-10-24-13-16/h4,6,8-10,12-13,17H,5,7,11,14-15H2,1-3H3,(H,25,28)/t17-/m0/s1

InChI Key

JOIWTEDZZMDKAU-KRWDZBQOSA-N

MDL Number (MFCD)

MFCD14845656

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

456.57

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.151

Distribution Coefficient, logD

1.148

Water Solubility, LogSw

-2.05

Polar Surface Area

81.320

Acid Dissociation Constant (pKa)

12.74

Base Dissociation Constant (pKb)

5.15

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

43.50

E203-1467 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Others
  • Kinases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with E203-1467 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E203-1467?
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What is the minimum amount of E203-1467 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E203-1467
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E203-1467
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E203-1467 available by request