E203-1470 Screening compound: N-(6-methyl-2-pyridyl)-1-[(1,3,3-trimethyl-2-oxo-2,3-dihydro-1H-indol-5-yl)sulfonyl]-3-piperidinecarboxamide

E203-1470 Screening compound: N-(6-methyl-2-pyridyl)-1-[(1,3,3-trimethyl-2-oxo-2,3-dihydro-1H-indol-5-yl)sulfonyl]-3-piperidinecarboxamide
E203-1470 Screening compound: N-(6-methyl-2-pyridyl)-1-[(1,3,3-trimethyl-2-oxo-2,3-dihydro-1H-indol-5-yl)sulfonyl]-3-piperidinecarboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound E203-1470
N-(6-methyl-2-pyridyl)-1-[(1,3,3-trimethyl-2-oxo-2,3-dihydro-1H-indol-5-yl)sulfonyl]-3-piperidinecarboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

E203-1470

Molecular Formula

C23H28N4O4S (C23 H28 N4 O4 S)

Compound Name

N-(6-methyl-2-pyridyl)-1-[(1,3,3-trimethyl-2-oxo-2,3-dihydro-1H-indol-5-yl)sulfonyl]-3-piperidinecarboxamide

IUPAC name

N-(6-methylpyridin-2-yl)-1-[(133-trimethyl-2-oxo-23-dihydro-1H-indol-5-yl)sulfonyl]piperidine-3-carboxamide

SMILES

CC(C)(c(cc(cc1)S(N(CCC2)CC2C(Nc2nc(C)ccc2)=O)(=O)=O)c1N1C)C1=O

InChI

InChI=1S/C23H28N4O4S/c1-15-7-5-9-20(24-15)25-21(28)16-8-6-12-27(14-16)32(30,31)17-10-11-19-18(13-17)23(2,3)22(29)26(19)4/h5,7,9-11,13,16H,6,8,12,14H2,1-4H3,(H,24,25,28)/t16-/m0/s1

InChI Key

MYHFNTIWVMWWKW-INIZCTEOSA-N

MDL Number (MFCD)

MFCD14845657

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

456.57

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.515

Distribution Coefficient, logD

2.513

Water Solubility, LogSw

-3.07

Polar Surface Area

79.469

Acid Dissociation Constant (pKa)

9.73

Base Dissociation Constant (pKb)

4.27

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

43.48

E203-1470 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Others
  • Kinases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with E203-1470 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound E203-1470?
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What is the minimum amount of E203-1470 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for E203-1470
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for E203-1470
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of E203-1470 available by request